Type 2 diabetes mellitus

Genetic polymorphisms of the TLR4 gene and their association with susceptibility to type 2 diabetes mellitus in the Chinese population

X. D. Fu, Sun, X. Q., Wang, H. Y., Guo, J. F., Zhang, G. Z., and Xu, Q. H., Genetic polymorphisms of the TLR4 gene and their association with susceptibility to type 2 diabetes mellitus in the Chinese population, vol. 12, pp. 3813-3820, 2013.

Toll-like receptor 4 (TLR4) is potentially an important gene affecting the susceptibility to type 2 diabetes mellitus (T2DM). The objective of this study was to evaluate whether genetic polymorphisms of the TLR4 gene are associated with T2DM susceptibility. This potential association was analyzed in 668 T2DM patients and 672 healthy controls by polymerase chain reaction-restriction fragment length polymorphism and DNA sequencing methods.

Pages

Subscribe to Type 2 diabetes mellitus