Type 2 diabetes mellitus

Association of VDR polymorphisms with type 2 diabetes mellitus in Chinese Han and Hui populations

J. R. Xu, Yang, Y., Liu, X. M., and Wang, Y. J., Association of VDR polymorphisms with type 2 diabetes mellitus in Chinese Han and Hui populations, vol. 13, pp. 9588-9598, 2014.

We investigated the association between vitamin D receptor (VDR) and susceptibility to type 2 diabetes mellitus (T2DM). Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) analysis was conducted to examine single nucleotide polymorphisms (SNPs) of the rs1544410 (BsmI, G>A), rs757343 (Tru9I, G>A), rs731236 (TaqI, T>C), and rs739837 (BglI, G>T) loci of the VDR gene in 334 healthy individuals (Hui 115, Han 219) and 355 T2DM patients (Hui 154, Han 201) living in the Ningxia Hui Autonomous Region of China.

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