Vascular injury

Gender difference in protein expression of vascular wall in mice exposed to chronic intermittent hypoxia: a preliminary study

Q. Y. Li, Feng, Y., Lin, Y. N., Li, M., Guo, Q., Gu, S. Y., Liu, J. L., Zhang, R. F., and Wan, H. Y., Gender difference in protein expression of vascular wall in mice exposed to chronic intermittent hypoxia: a preliminary study, vol. 13, pp. 8489-8501, 2014.

Obstructive sleep apnea (OSA) is an independent risk factor for cardiovascular diseases such as systemic arterial hypertension, ischemic heart disease, stroke, heart failure, atrial fibrillation, and cardiac sudden death. The pathogenesis of cardiovascular disease in OSA is thought to be induced primarily by chronic intermittent hypoxia (CIH), a specific pattern of change in oxygenation during sleep. However, the underlying mechanisms of CIH-induced vasculature injury and gender differences are not well documented.

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