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Metagenomic study of single-nucleotide polymorphism within candidate genes associated with type 2 diabetes in

P. N. Mukhopadhyaya, Acharya, A., Chavan, Y., Purohit, S. S., and Mutha, A., Metagenomic study of single-nucleotide polymorphism within candidate genes associated with type 2 diabetes in, vol. 9, pp. 2060-2068, 2010.

A population-based study was undertaken to evaluate linkage between single-nucleotide polymorphisms known as risk factors and type 2 diabetes in an Indian population. The study population was comprised of 40 normal glucose-tolerant individuals (21 males and 19 females) and 40 type 2 diabetes patients (21 males and 19 females). The genes and their corresponding single-nucleotide polymorphisms that we screened were VDR (rs 731236 and rs 1544410), IL-6 (rs 1800795), TCF7L2 (rs 7903146) and TNF-α (rs 1800629).

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