VDR polymorphisms

Association analysis of vitamin D receptor gene polymorphisms and bone mineral density in postmenopausal Mexican-Mestizo women

A. González-Mercado, Sánchez-López, J. Y., Regla-Nava, J. A., Gámez-Nava, J. I., González-López, L., Duran-Gonzalez, J., Celis, A., Perea-Díaz, F. J., Salazar-Páramo, M., and Ibarra, B., Association analysis of vitamin D receptor gene polymorphisms and bone mineral density in postmenopausal Mexican-Mestizo women, vol. 12, pp. 2755-2763, 2013.

We investigated associations between vitamin D receptor (VDR) gene polymorphisms, FokI T>C (rs2228570), BsmI G>A (rs1544410), ApaI G>T (rs7975232), and TaqI T>C (rs731236), with bone mineral density (BMD) in postmenopausal Mexican-Mestizo women. Three hundred and twenty postmenopausal women participated, who were classified according to World Health Organization criteria as non-osteoporotic (Non-OP; N = 88), osteopenic (Opn; N = 144), and osteoporotic (OP; N = 88).

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