VEGF

Vascular endothelial growth factor gene polymorphisms and colorectal cancer risk: a meta-analysis

L. P. Zhou, Luan, H., Dong, X. H., Jin, G. J., Man, D. L., and Shang, H., Vascular endothelial growth factor gene polymorphisms and colorectal cancer risk: a meta-analysis, vol. 10, pp. 3674-3688, 2011.

Vascular endothelial growth factor (VEGF) is an endothelial cell-specific mitogen involved in a number of pathologic processes, including angiogenesis, tumor growth and metastasis. Polymorphisms of the VEGF gene have been associated with susceptibility to colorectal cancer (CRC). However, the specific association still remains controversial. We made a meta-analysis of the association between VEGF gene polymorphisms and CRC risk. Only eight case-control studies were retrieved, with a total of 2337 CRC patients and 2032 healthy controls.

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