VEGF

Role of VEGF gene polymorphisms in the clinical outcome of non-small cell lung cancer

N. Chen, Ma, C. N., Zhao, M., and Zhang, Y. J., Role of VEGF gene polymorphisms in the clinical outcome of non-small cell lung cancer, vol. 14, pp. 16006-16011, 2015.

This report details a study conducted to assess the role of VEGF gene polymorphisms in the prognosis of advanced non-small cell lung carcinoma (NSCLC). Samples obtained from 210 advanced NSCLC patients admitted at the Huaihe Hospital of Henan University between January 2010 and December 2011 were recruited for this study. The VEGF -2578C/A (rs699947), +936C/T (rs3025039), and -634G/C (rs2010963) genotypes were analyzed by polymerase chain reaction-restriction fragment length polymorphism.

Influence of vascular endothelial growth factor and alpha-fetoprotein on hepatocellular carcinoma

E. Y. Yvamoto, Ferreira, R. F., Nogueira, V., Pinhel, M. A. S., Tenani, G. D., Andrade, J. G. S. C., Baitello, M. E. L., Gregório, M. L., Fucuta, P. S., Silva, R. F., Souza, D. R. S., and Silva, R. C. M. A., Influence of vascular endothelial growth factor and alpha-fetoprotein on hepatocellular carcinoma, vol. 14, pp. 17453-17462, 2015.

We evaluated the influence of the vascular endothelial growth factor (VEGF) -C936T polymorphism on prognosis of hepatocellular carcinoma (HCC), cirrhosis, and hepatitis C virus (HCV) infection. Serum VEGF and alpha-fetoprotein (AFP) levels were determined and used to characterize sensitivity and specificity. A total of 285 subjects were studied: 68 HCC, 118 cirrhosis, 43 HCV, and 56 healthy controls.

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