Virulence

Carbon source-induced changes in the physiology of the cacao pathogen Moniliophthora perniciosa (Basidiomycetes) affect mycelial morphology and secretion of necrosis-inducing proteins

F. C. Alvim, Mattos, E. M., Pirovani, C. P., Gramacho, K., Pungartnik, C., Brendel, M., Cascardo, J. C. M., and Vincentz, M., Carbon source-induced changes in the physiology of the cacao pathogen Moniliophthora perniciosa (Basidiomycetes) affect mycelial morphology and secretion of necrosis-inducing proteins, vol. 8, pp. 1035-1050, 2009.

Quantitative and qualitative relationships were found between secreted proteins and their activity, and the hyphal morphol­ogy of Moniliophthora perniciosa, the causal agent of witches’ broom disease in Theobroma cacao. This fungus was grown on fermentable and non-fermentable carbon sources; significant differences in myce­lial morphology were observed and correlated with the carbon source.

Virulence insights from the Paracoccidioides brasiliensis transcriptome

A. Henrique Tavares, Silva, S. Souza, Bernardes, V. Vilmar, Maranhão, A. Queiróz, Maranhão, A. Queiróz, Kyaw, C. Maria Kyaw, Poças-Fonseca, M., and Silva-Pereira, I., Virulence insights from the Paracoccidioides brasiliensis transcriptome, vol. 4. pp. 372-389, 2005.

Paracoccidioides brasiliensis, the etiologic agent of paracoccidioidomycosis, is a dimorphic fungus, which is found as mycelia at 22-26ºC and as yeasts at 37ºC. A remarkable feature common to several pathogenic fungi is their ability to differentiate from mycelium to yeast morphologies, or vice-versa. Although P. brasiliensis is a recognized pathogen for humans, little is known about its virulence genes. In this sense, we performed a search for putative virulence genes in the P. brasiliensis transcriptome.

Chromobacterium violaceum genome: molecular mechanisms associated with pathogenicity

C. F. Alves de Brito, Carvalho, C. M. B., Santos, F. R., Gazzinelli, R. T., Oliveira, S. C., Azevedo, V., and Teixeira, S. M. R., Chromobacterium violaceum genome: molecular mechanisms associated with pathogenicity, vol. 3, pp. 148-161, 2004.

Chromobacterium violaceum is a versatile, Gram-negative β-protebacterium that grows in a variety of ecosystems in tropical and subtropical areas, such as the water and borders of the Negro River, in the Amazon region of Brazil. Although it is a saprophyte and is generally considered non-pathogenic, sporadic cases of human infection have been described, mainly in young children and in immunodeficient individuals. Although rare, infections with C. violaceum are characterized by rapid dissemination and high mortality. With the complete genome sequence of C.

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