Vitamin D receptor

Vitamin D receptor gene FokI, TaqI, BsmI, and ApaI polymorphisms and susceptibility to pulmonary tuberculosis: a meta-analysis

Y. H. Lee and Song, G. G., Vitamin D receptor gene FokI, TaqI, BsmI, and ApaI polymorphisms and susceptibility to pulmonary tuberculosis: a meta-analysis, vol. 14, pp. 9118-9129, 2015.

The aim of this study was to determine whether vitamin D receptor (VDR) genetic polymorphisms are associated with the susceptibility to pulmonary tuberculosis (PTB). MEDLINE and Embase databases and manual literature searches were used. A meta-analysis was conducted on the associations between the VDR FokI, TaqI, BsmI, and ApaI polymorphisms and PTB susceptibility.

Analysis of the association between polymorphisms in the vitamin D receptor (VDR) gene and dental caries in a Chinese population

X. P. Hu, Li, Z. Q., Zhou, J. Y., Yu, Z. H., Zhang, J. M., and Guo, M. L., Analysis of the association between polymorphisms in the vitamin D receptor (VDR) gene and dental caries in a Chinese population, vol. 14, pp. 11631-11638, 2015.

Environmental influences on the development and progression of dental caries are well known; however, there is little evidence of a genetic component imparting susceptibility to dental caries. The aim of this study was to investigate the relationship between a single nucleotide polymorphism in the vitamin D receptor TaqI locus and dental caries susceptibility in a Chinese population.

Vitamin D receptor FokI gene polymorphism and tuberculosis susceptibility: a meta-analysis

Y. P. Sun and Cai, Q. S., Vitamin D receptor FokI gene polymorphism and tuberculosis susceptibility: a meta-analysis, vol. 14, pp. 6156-6163, 2015.

Numerous studies have evaluated the association between FokI polymorphisms in the vitamin D receptor (VDR) gene and tuberculosis risk. However, the specific association remains controversial. In this study, we performed a meta-analysis to assess the association between the VDR gene FokI polymorphism and tuberculosis. Published studies from the PubMed and Embase databases were retrieved. The pooled odds ratio (OR) with 95% confidence interval (CI) was calculated using fixed- or random-effect models.

Polymorphisms of the vitamin D receptor gene and the risk of inflammatory bowel disease: a meta-analysis

L. Wang, Wang, Z. T., Hu, J. J., Fan, R., Zhou, J., and Zhong, J., Polymorphisms of the vitamin D receptor gene and the risk of inflammatory bowel disease: a meta-analysis, vol. 13, pp. 2598-2610, 2014.

The gene encoding vitamin D receptor (VDR) is recognized as a promising candidate for indicating the development of inflammatory bowel disease (IBD). Four genetic polymorphisms (ApaI, BsmI, FokI, TaqI) in VDR have been widely evaluated to determine their association with IBD, and the results of these evaluations are often inconsistent. Therefore, we conducted a meta-analysis to shed some light on this issue and explored the sources of the heterogeneity between studies.

Vitamin D receptor genetic variants are associated with susceptibility of gallbladder adenocarcinoma in a Chinese cohort

Z. Li, Yuan, W. T., Ning, S. J., and Zhang, S. J., Vitamin D receptor genetic variants are associated with susceptibility of gallbladder adenocarcinoma in a Chinese cohort, vol. 13, pp. 5387-5394, 2014.

The aim of this study was to test for the possible association between vitamin D receptor (VDR) genetic variants and susceptibility to gallbladder cancer (GBC). A total of 291 GBC cases were recruited and 396 gender- and age-matched healthy volunteers were enrolled as controls. The VDR gene polymorphisms were determined in all subjects. The genotype and the allele frequencies of ApaI, BsmI, and TaqI polymorphisms were not significantly different between GBC subjects and controls.

Association of vitamin D receptor BsmI gene polymorphism with risk of low bone mineral density in post-menopausal women: a meta-analysis

C. Ma, Zhou, Q. L., Deng, Y. J., Liang, X., Wu, D. P., and Dong, Y. Z., Association of vitamin D receptor BsmI gene polymorphism with risk of low bone mineral density in post-menopausal women: a meta-analysis, vol. 13, pp. 7791-7799, 2014.

The vitamin D receptor BsmI gene polymorphism is reportedly associated with low bone mineral density (BMD) in postmenopausal women, but results from previous studies are conflicting. In the present study, we investigated the association between this polymorphism and the risk of low BMD through a meta-analysis of published studies. A literature search of the Pubmed, Embase, and CNKI databases from inception through July 2013 was conducted. The meta-analysis was performed using the STATA 12.0 software.

Association of VDR polymorphisms with type 2 diabetes mellitus in Chinese Han and Hui populations

J. R. Xu, Yang, Y., Liu, X. M., and Wang, Y. J., Association of VDR polymorphisms with type 2 diabetes mellitus in Chinese Han and Hui populations, vol. 13, pp. 9588-9598, 2014.

We investigated the association between vitamin D receptor (VDR) and susceptibility to type 2 diabetes mellitus (T2DM). Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) analysis was conducted to examine single nucleotide polymorphisms (SNPs) of the rs1544410 (BsmI, G>A), rs757343 (Tru9I, G>A), rs731236 (TaqI, T>C), and rs739837 (BglI, G>T) loci of the VDR gene in 334 healthy individuals (Hui 115, Han 219) and 355 T2DM patients (Hui 154, Han 201) living in the Ningxia Hui Autonomous Region of China.

Subscribe to Vitamin D receptor