Vitamin D receptor

Assessment of the link between Vitamin D receptor TaqI gene polymorphism and periodontitis: a meta-analysis in a Chinese population

X. W. Ji, Wang, Y., Cao, C., Zhong, L. J., Ji, X. W., Wang, Y., Cao, C., and Zhong, L. J., Assessment of the link between Vitamin D receptor TaqI gene polymorphism and periodontitis: a meta-analysis in a Chinese population, vol. 15, p. -, 2016.

Although a number of studies have been conducted to determine the association between vitamin D receptor (VDR) TaqI polymorphism and periodontitis in the Chinese population, this association remains elusive. To assess the influence of VDR TaqI polymorphism on the risk of periodontitis, a meta-analysis was performed in a Chinese population. Relevant studies were identified using the databases PubMed, Springer Link, Ovid, Chinese Wanfang Data Knowledge Service Platform, Chinese National Knowledge Infrastructure, and Chinese Biology Medicine, through January 2016.

Lack of association between the vitamin D receptor polymorphism rs2228570 and chronic periodontitis in a Han Chinese population

X. Wang, Zhang, T. L., and Chen, D., Lack of association between the vitamin D receptor polymorphism rs2228570 and chronic periodontitis in a Han Chinese population, vol. 14, pp. 12299-12305, 2015.

The vitamin D receptor (VDR) is involved in the immune response and bone metabolism, both of which are implicated in the pathogenesis of chronic periodontitis (CP). In this study, we investigated the association between the VDR single nucleotide polymorphism rs2228570 and CP susceptibility in a Han Chinese population consisting of 440 moderate or severe CP patients and 324 controls. Genomic DNA was extracted from buccal epithelial cells and genotyped using matrix-assisted laser desorption/ionization time-of-flight-mass spectrometry.

Analysis of the association between polymorphisms in the vitamin D receptor (VDR) gene and dental caries in a Chinese population

X. P. Hu, Li, Z. Q., Zhou, J. Y., Yu, Z. H., Zhang, J. M., and Guo, M. L., Analysis of the association between polymorphisms in the vitamin D receptor (VDR) gene and dental caries in a Chinese population, vol. 14, pp. 11631-11638, 2015.

Environmental influences on the development and progression of dental caries are well known; however, there is little evidence of a genetic component imparting susceptibility to dental caries. The aim of this study was to investigate the relationship between a single nucleotide polymorphism in the vitamin D receptor TaqI locus and dental caries susceptibility in a Chinese population.

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