Xeroderma pigmentosum group F

Association between ERCC1 and XPF polymorphisms and risk of colorectal cancer

H. Yang, Li, G., and Li, W. F., Association between ERCC1 and XPF polymorphisms and risk of colorectal cancer, vol. 14, pp. 700-705, 2015.

We conducted a hospital-based case-control study to evaluate the association between polymorphisms in excision repair cross-complementing group 1-xeroderma pigmentosum group F (ERCC1-XPF) variants and the risk of colorectal cancer in a Chinese population. Genotyping of the ERCC1 rs2298881 and rs11615 and XPF rs2276466 polymorphisms were detected by polymerase chain reaction-restriction fragment length polymorphism. Colorectal cancer cases were more likely to be smokers, consume alcohol, have higher energy intake, and have a family history of cancer.

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