XPD

Implication of polymorphisms in DNA repair genes with an increased risk of hepatocellular carcinoma

J. S. Wu, Chen, Y. P., Wang, L. C., Yang, Y. J., Deng, C. W., Hou, B. X., He, Z. L., and Chen, J. X., Implication of polymorphisms in DNA repair genes with an increased risk of hepatocellular carcinoma, vol. 13, pp. 3812-3818, 2014.

We explored the association between 4 XRCC1 (Arg194Trp and Arg399Gln) and XPD (Asp312Asn and Lys751Gln) polymorphisms with the development and prognosis of hepatocellular carcinoma (HCC). A total of 218 cases with HCC and 277 healthy controls were included in the study. Genotyping of the XRCC1 (Arg194Trp and Arg399Gln) and XPD (Asp312Asn and Lys751Gln) polymorphisms was performed in a 384-well plate format on the Sequenom MassARRAY platform.

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