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L. Zhang, Yang, W. P., Wu, L. Y., Zhu, X., Wei, C. Y., Zhang, L., Yang, W. P., Wu, L. Y., Zhu, X., and Wei, C. Y., Expression and clinical significance of Kelch-like epichlorohydrin-associated protein 1 in breast cancer, vol. 15, p. -, 2016.
L. Zhang, Yang, W. P., Wu, L. Y., Zhu, X., Wei, C. Y., Zhang, L., Yang, W. P., Wu, L. Y., Zhu, X., and Wei, C. Y., Expression and clinical significance of Kelch-like epichlorohydrin-associated protein 1 in breast cancer, vol. 15, p. -, 2016.
L. Zheng, Qi, Y. X., Liu, S., Shi, M. L., and Yang, W. P., miR-129b suppresses cell proliferation in the human lung cancer cell lines A549 and H1299, vol. 15, no. 4, p. -, 2016.
Conflicts of interestThe authors declare no conflict of interest.ACKNOWLEDGMENTSWe thank all of our lab members for helpful discussions and critical comments on this study. Research supported by the People’s Hospital of Laiwu City, and was approved by the Medical Scientific Research Foundation of Guangdong Province (Grant #B2014360) as well as the Scientific Research Project of Shenzhen Health Bureau (Grant #201402043) REFERENCESAlmeida MI, Reis RM, Calin GA, et al (2011). MicroRNA history: discovery, recent applications, and next frontiers. Mutat. Res. 717: 1-8. Bandres E, Agirre X, Bitarte N, Ramirez N, et al (2009). Epigenetic regulation of microRNA expression in colorectal cancer. Int. J. Cancer 125: 2737-2743. Calin GA, Sevignani C, Dumitru CD, Hyslop T, et al (2004). Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers. Proc. Natl. Acad. Sci. USA 101: 2999-3004. Chen X, Zhang L, Zhang T, Hao M, et al (2013). Methylation-mediated repression of microRNA 129-2 enhances oncogenic SOX4 expression in HCC. Liver Int. 33: 476-486. Di Leva G, Croce CM, et al (2010). Roles of small RNAs in tumor formation. Trends Mol. Med. 16: 257-267. Garzon R, Calin GA, Croce CM, et al (2009). MicroRNAs in Cancer. Annu. Rev. Med. 60: 167-179. Hayashita Y, Osada H, Tatematsu Y, Yamada H, et al (2005). A polycistronic microRNA cluster, miR-17-92, is overexpressed in human lung cancers and enhances cell proliferation. Cancer Res. 65: 9628-9632. Hu Z, Chen X, Zhao Y, Tian T, et al (2010). Serum microRNA signatures identified in a genome-wide serum microRNA expression profiling predict survival of non-small-cell lung cancer. J. Clin. Oncol. 28: 1721-1726. Inamura K, Togashi Y, Nomura K, Ninomiya H, et al (2007). let-7 microRNA expression is reduced in bronchioloalveolar carcinoma, a non-invasive carcinoma, and is not correlated with prognosis. Lung Cancer 58: 392-396. Johnson SM, Grosshans H, Shingara J, Byrom M, et al (2005). RAS is regulated by the let-7 microRNA family. Cell 120: 635-647. Karaayvaz M, Zhai H, Ju J, et al (2013). miR-129 promotes apoptosis and enhances chemosensitivity to 5-fluorouracil in colorectal cancer. Cell Death Dis. 4: e659. Katada T, Ishiguro H, Kuwabara Y, Kimura M, et al (2009). microRNA expression profile in undifferentiated gastric cancer. Int. J. Oncol. 34: 537-542. Krol J, Loedige I, Filipowicz W, et al (2010). The widespread regulation of microRNA biogenesis, function and decay. Nat. Rev. Genet. 11: 597-610. Liu Y, Hei Y, Shu Q, Dong J, et al (2012). VCP/p97, down-regulated by microRNA-129-5p, could regulate the progression of hepatocellular carcinoma. PLoS One 7: e35800. Lu CY, Lin KY, Tien MT, Wu CT, et al (2013). Frequent DNA methylation of MiR-129-2 and its potential clinical implication in hepatocellular carcinoma. Genes Chromosomes Cancer 52: 636-643. Malvezzi M, Bertuccio P, Levi F, La Vecchia C, et al (2013). European cancer mortality predictions for the year 2013. Ann. Oncol. 24: 792-800. Munker R, Calin GA, et al (2011). MicroRNA profiling in cancer. Clin. Sci. 121: 141-158. Poghosyan H, Sheldon LK, Leveille SG, Cooley ME, et al (2013). Health-related quality of life after surgical treatment in patients with non-small cell lung cancer: a systematic review. Lung Cancer 81: 11-26. Siegel R, Naishadham D, Jemal A, et al (2013). Cancer statistics, 2013. CA Cancer J. Clin. 63: 11-30. Spira A, Ettinger DS, et al (2004). Multidisciplinary management of lung cancer. N. Engl. J. Med. 350: 379-392. Takamizawa J, Konishi H, Yanagisawa K, Tomida S, et al (2004). Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival. Cancer Res. 64: 3753-3756. Tsai KW, Wu CW, Hu LY, Li SC, et al (2011). Epigenetic regulation of miR-34b and miR-129 expression in gastric cancer. Int. J. Cancer 129: 2600-2610. Wang R, Wang ZX, Yang JS, Pan X, et al (2011). MicroRNA-451 functions as a tumor suppressor in human non-small cell lung cancer by targeting ras-related protein 14 (RAB14). Oncogene 30: 2644-2658. Yanaihara N, Caplen N, Bowman E, Seike M, et al (2006). Unique microRNA molecular profiles in lung cancer diagnosis and prognosis. Cancer Cell 9: 189-198. Yu X, Song H, Xia T, Han S, et al (2013). Growth inhibitory effects of three miR-129 family members on gastric cancer. Gene 532: 87-93. Zhang HC, Song YF, Ye J, Lai GX, et al. (2016). MicroRNA-154 functions as a tumor suppressor and directly targets HMGA2 in human non-small cell lung cancer. Genet. Mol. Res. 15: gmr.15028173. Zhang J, Xue ZQ, Chu XY, Wang YX, et al (2012). Surgical treatment and prognosis of octogenarians with non-small cell lung cancer. Asian Pac. J. Trop. Med. 5: 465-468. Zhou X, Zhang L, Zheng B, Yan Y, et al (2016). MicroRNA-761 is upregulated in hepatocellular carcinoma and regulates tumorigenesis by targeting Mitofusin-2. Cancer Sci. 107: 424-432.