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2012
C. C. M. Otenio, Fonseca, I., Martins, M. F., Ribeiro, L. C., Assis, N. M. S. P., Ferreira, A. P., and Ribeiro, R. A., Expression of IL-1, IL-6, TNF-α, and iNOS in pregnant women with periodontal disease, vol. 11, pp. 4468-4478, 2012.
Agueda A, Ramon JM, Manau C, Guerrero A, et al. (2008). Periodontal disease as a risk factor for adverse pregnancy outcomes: a prospective cohort study. J. Clin. Periodontol. 35: 16-22. PMid:18034850   Albandar JM and Rams TE (2002). Global epidemiology of periodontal diseases: an overview. Periodontol. 2000 29: 7-10. http://dx.doi.org/10.1034/j.1600-0757.2002.290101.x PMid:12102700   Andrukhov O, Ulm C, Reischl H, Nguyen PQ, et al. (2011). Serum cytokine levels in periodontitis patients in relation to the bacterial load. J. Periodontol. 82: 885-892. http://dx.doi.org/10.1902/jop.2010.100425 PMid:21138356   Armitage GC (1999). Development of a classification system for periodontal diseases and conditions. Ann. Periodontol. 4: 1-6. http://dx.doi.org/10.1902/annals.1999.4.1.1 PMid:10863370   Associação Brasileira de Empresas de Pesquisa - ABEP (2003). Critério de Classificação Econômica Brasil. Available at [http//:www.abep.org]. Accessed September, 2011.   Assuma R, Oates T, Cochran D, Amar S, et al. (1998). IL-1 and TNF antagonists inhibit the inflammatory response and bone loss in experimental periodontitis. J. Immunol. 160: 403-409. PMid:9551997   Beharka AA, Meydani M, Wu D, Leka LS, et al. (2001). Interleukin-6 production does not increase with age. J. Gerontol. A Biol. Sci. Med. Sci. 56: B81-B88. http://dx.doi.org/10.1093/gerona/56.2.B81 PMid:11213271   Bickel M, Axtelius B, Solioz C and Attstrom R (2001). Cytokine gene expression in chronic periodontitis. J. Clin. Periodontol. 28: 840-847. http://dx.doi.org/10.1034/j.1600-051x.2001.028009840.x PMid:11493353   Carrillo-de-Albornoz A, Figuero E, Herrera D, Cuesta P, et al. (2012). Gingival changes during pregnancy: III. Impact of clinical, microbiological, immunological and socio-demographic factors on gingival inflammation. J. Clin. Periodontol. 39: 272-283. http://dx.doi.org/10.1111/j.1600-051X.2011.01800.x PMid:22092526   Chen YW, Umeda M, Nagasawa T, Takeuchi Y, et al. (2008). Periodontitis may increase the risk of peripheral arterial disease. Eur. J. Vasc. Endovasc. Surg. 35: 153-158. http://dx.doi.org/10.1016/j.ejvs.2007.08.016 PMid:17964192   Douglas SD, Lynch KG and Lai JP (2008). Neurokinin-1 receptor mRNA expression differences in brains of HIV-infected individuals. J. Neurol. Sci. 272: 174-177. http://dx.doi.org/10.1016/j.jns.2008.04.025 PMid:18572194 PMCid:2551749   Ejeil AL, Gaultier F, Igondjo-Tchen S, Senni K, et al. (2003). Are cytokines linked to collagen breakdown during periodontal disease progression? J. Periodontol. 74: 196-201. http://dx.doi.org/10.1902/jop.2003.74.2.196 PMid:12666708   Faizuddin M, Bharathi SH and Rohini NV (2003). Estimation of interleukin-1beta levels in the gingival crevicular fluid in health and in inflammatory periodontal disease. J. Periodontal Res. 38: 111-114. http://dx.doi.org/10.1034/j.1600-0765.2003.01649.x PMid:12608903   Figuero E, Carrillo-de-Albornoz A, Herrera D and Bascones-Martinez A (2010). Gingival changes during pregnancy: I. Influence of hormonal variations on clinical and immunological parameters. J. Clin. Periodontol. 37: 220-229. http://dx.doi.org/10.1111/j.1600-051X.2009.01516.x PMid:20070862   Giulietti A, Overbergh L, Valckx D, Decallonne B, et al. (2001). An overview of real-time quantitative PCR: applications to quantify cytokine gene expression. Methods 25: 386-401. http://dx.doi.org/10.1006/meth.2001.1261 PMid:11846608   Górska R, Gregorek H, Kowalski J, Laskus-Perendyk A, et al. (2003). Relationship between clinical parameters and cytokine profiles in inflamed gingival tissue and serum samples from patients with chronic periodontitis. J. Clin. Periodontol. 30: 1046-1052. http://dx.doi.org/10.1046/j.0303-6979.2003.00425.x PMid:15002890   Gürsoy M, Pajukanta R, Sorsa T and Kononen E (2008). Clinical changes in periodontium during pregnancy and post-partum. J. Clin. Periodontol. 35: 576-583. http://dx.doi.org/10.1111/j.1600-051X.2008.01236.x PMid:18430046   Hirose M, Ishihara K, Saito A, Nakagawa T, et al. (2001). Expression of cytokines and inducible nitric oxide synthase in inflamed gingival tissue. J. Periodontol. 72: 590-597. http://dx.doi.org/10.1902/jop.2001.72.5.590 PMid:11394393   Katz Y, Nadiv O and Beer Y (2001). Interleukin-17 enhances tumor necrosis factor alpha-induced synthesis of interleukins 1,6, and 8 in skin and synovial fibroblasts: a possible role as a "fine-tuning cytokine" in inflammation processes. Arthritis Rheum. 44: 2176-2184. http://dx.doi.org/10.1002/1529-0131(200109)44:9<2176::AID-ART371>3.0.CO;2-4   Kendall HK, Haase HR, Li H, Xiao Y, et al. (2000). Nitric oxide synthase type-II is synthesized by human gingival tissue and cultured human gingival fibroblasts. J. Periodontal Res. 35: 194-200. http://dx.doi.org/10.1034/j.1600-0765.2000.035004194.x PMid:10983879   Kornman KS and Loesche WJ (1980). The subgingival microbial flora during pregnancy. J. Periodontal Res. 15: 111-122. http://dx.doi.org/10.1111/j.1600-0765.1980.tb00265.x PMid:6103927   Laine MA (2002). Effect of pregnancy on periodontal and dental health. Acta Odontol. Scand. 60: 257-264. http://dx.doi.org/10.1080/00016350260248210 PMid:12418714   Lapp CA, Thomas ME and Lewis JB (1995). Modulation by progesterone of interleukin-6 production by gingival fibroblasts. J. Periodontol. 66: 279-284. http://dx.doi.org/10.1902/jop.1995.66.4.279 PMid:7782982   Lappin DF, Kjeldsen M, Sander L and Kinane DF (2000). Inducible nitric oxide synthase expression in periodontitis. J. Periodontal Res. 35: 369-373. http://dx.doi.org/10.1034/j.1600-0765.2000.035006369.x PMid:11144410   Lö YJ, Liu CM, Wong MY, Hou LT, et al. (1999). Interleukin 1beta-secreting cells in inflamed gingival tissue of adult periodontitis patients. Cytokine 11: 626-633. http://dx.doi.org/10.1006/cyto.1999.0448 PMid:10433811   Lopatin DE, Kornman KS and Loesche WJ (1980). Modulation of immunoreactivity to periodontal disease-associated microorganisms during pregnancy. Infect. Immun. 28: 713-718. PMid:7399691 PMCid:551009   López NJ, Smith PC and Gutierrez J (2002). Higher risk of preterm birth and low birth weight in women with periodontal disease. J. Dent. Res. 81: 58-63. http://dx.doi.org/10.1177/154405910208100113 PMid:11820369   Miyagi M, Morishita M and Iwamoto Y (1993). Effects of sex hormones on production of prostaglandin E2 by human peripheral monocytes. J. Periodontol. 64: 1075-1078. http://dx.doi.org/10.1902/jop.1993.64.11.1075 PMid:8295094   Moreira PR, Lima PM, Sathler KO, Imanishi SA, et al. (2007). Interleukin-6 expression and gene polymorphism are associated with severity of periodontal disease in a sample of Brazilian individuals. Clin. Exp. Immunol. 148: 119-126. http://dx.doi.org/10.1111/j.1365-2249.2007.03327.x PMid:17286759 PMCid:1868861   Morishita M, Miyagi M and Iwamoto Y (1999). Effects of sex hormones on production of interleukin-1 by human peripheral monocytes. J. Periodontol. 70: 757-760. http://dx.doi.org/10.1902/jop.1999.70.7.757 PMid:10440637   Mysliwska J, Bryl E, Foerster J and Mysliwski A (1998). Increase of interleukin 6 and decrease of interleukin 2 production during the ageing process are influenced by the health status. Mech. Ageing Dev. 100: 313-328. http://dx.doi.org/10.1016/S0047-6374(97)00154-1   Overbergh L, Giulietti A, Valckx D, Decallonne R, et al. (2003). The use of real-time reverse transcriptase PCR for the quantification of cytokine gene expression. J. Biomol. Tech. 14: 33-43. PMid:12901609 PMCid:2279895   Pan Z, Guzeldemir E, Toygar HU, Bal N, et al. (2010). Nitric oxide synthase in gingival tissues of patients with chronic periodontitis and with and without diabetes. J. Periodontol. 81: 109-120. http://dx.doi.org/10.1902/jop.2009.090454 PMid:20059423   Parwani SR, Chitnis PJ and Parwani RN (2012). Salivary nitric oxide levels in inflammatory periodontal disease - a case-control and interventional study. Int. J. Dent. Hyg. 10: 67-73. http://dx.doi.org/10.1111/j.1601-5037.2011.00508.x PMid:21564536   Rausch-Fan X and Matejka M (2001). From plaque formation to periodontal disease, is there a role for nitric oxide? Eur. J. Clin. Invest. 31: 833-835. http://dx.doi.org/10.1046/j.1365-2362.2001.00903.x PMid:11737219   Reher VG, Zenobio EG, Costa FO, Reher P, et al. (2007). Nitric oxide levels in saliva increase with severity of chronic periodontitis. J. Oral Sci. 49: 271-276. http://dx.doi.org/10.2334/josnusd.49.271 PMid:18195509   Teng YT (2006). Protective and destructive immunity in the periodontium: Part 1 - innate and humoral immunity and the periodontium. J. Dent. Res. 85: 198-208. http://dx.doi.org/10.1177/154405910608500301 PMid:16498065   Tobón-Arroyave SI, Jaramillo-Gonzalez PE and Isaza-Guzman DM (2008). Correlation between salivary IL-1beta levels and periodontal clinical status. Arch. Oral Biol. 53: 346-352. http://dx.doi.org/10.1016/j.archoralbio.2007.11.005 PMid:18155182   Vettore MV, Leal M, Leao AT, da Silva AM, et al. (2008). The relationship between periodontitis and preterm low birthweight. J. Dent. Res. 87: 73-78. http://dx.doi.org/10.1177/154405910808700113 PMid:18096898   Yamazaki K, Honda T, Oda T, Ueki-Maruyama K, et al. (2005). Effect of periodontal treatment on the C-reactive protein and proinflammatory cytokine levels in Japanese periodontitis patients. J. Periodontal Res. 40: 53-58. http://dx.doi.org/10.1111/j.1600-0765.2004.00772.x PMid:15613080
A. M. Auad, Martins, M. F., Fonseca, I., Paula-Moraes, S. V., Kopp, M. M., and Cordeiro, M. C., Spittle protein profile of Mahanarva spectabilis (Hemiptera: Cercopidae) fed various elephant grass genotypes, vol. 11, pp. 3601-3606, 2012.
Auad AM, Simões AD, Pereira AV, Braga ALF, et al. (2007). Seleção de genótipos de capim-elefante quanto à resistência à cigarrinha-das-pastagens. Pesq. Agropec. Bras. 42: 1077-1081. http://dx.doi.org/10.1590/S0100-204X2007000800003   Cardona C, Miles JW and Sotelo G (1999). An Improved Methodology for massive screening of Brachiaria spp. Genotypes for resistance to Aeneolamia varia (Homoptera: Cercopidae). J. Econ. Entomol. 92: 490-496.   Cardona C, Fory P, Sotelo G, Pabon A, et al. (2004). Antibiosis and tolerance to five species of spittlebug (Homoptera: Cercopidae) in Brachiaria spp.: implications for breeding for resistance. J. Econ. Entomol. 97: 635-645. http://dx.doi.org/10.1603/0022-0493-97.2.635 PMid:15154493   Kato K (1958). Origin and composition of spittle made by spittlebugs. Sci. Rep. Saitama Univ. Ser. B. 3: 33-53.   Marshall AT (1965). Batelli glands of cercopoid nymphs (Homoptera). Nature 205: 925. http://dx.doi.org/10.1038/205925b0   Miles JW, Cardona C and Sotelo G (2006). Recurrent selection in a synthetic brachiariagrass population improves resistance to three spittlebug species. Crop Sci. 46: 1088-1093. http://dx.doi.org/10.2135/cropsci2005.06-0101   Rohlf FJ (2000). NTSYSpc: Numerical Taxonomy and Multivariate Analysis System. Version 2.1. Exeter Software, New York.   Rossignol M, Peltier JB, Mock HP, Matros A, et al. (2006). Plant proteome analysis: a 2004-2006 update. Proteomics 6: 5529-5548. http://dx.doi.org/10.1002/pmic.200600260 PMid:16991197   Sokal RR and Michener C (1958). A statistical method for evaluating systematic relationships. Univ. Kansas Sci. Bull. 38: 1409-1438.   Sokal RR and Rohlf FJ (1962). The comparison of dendrograms by objective methods. Taxon 11: 30-40. http://dx.doi.org/10.2307/1217208   Sotelo PA, Miller MF, Cardona C, Miles JW, et al. (2008). Sublethal effects of antibiosis resistance on the reproductive biology of two spittlebug (Hemiptera: Cercopidae) species affecting Brachiaria spp. J. Econ. Entomol. 101: 564-568. http://dx.doi.org/10.1603/0022-0493(2008)101[564:SEOARO]2.0.CO;2   Souza Sobrinho F, Auad AM and Lédo FJS (2010). Genetic variability in Brachiaria ruziziensis for resistance to spittlebugs. Crop Breed. Appl. Biotechnol. 10: 83-88.   Valério JR (2009). Cigarrinhas-das-pastagens. Vol.1. Embrapa Gado de Corte, Campo Grade.   Valério JR, Jeller H and Peixer J (1997). Seleção de introduções do gênero Brachiaria (Griseb) resistentes à cigarrinha Zulia entreriana (Berg) (Homoptera: Cercopidae). An. Soc. Entomol. Bras. 2: 383-387. http://dx.doi.org/10.1590/S0301-80591997000200023
C. S. Nascimento, Peixoto, J. O., Verardo, L. L., Campos, C. F., Weller, M. M. C., Faria, V. R., Botelho, M. E., Martins, M. F., Machado, M. A., Silva, F. F., Lopes, P. S., and Guimarães, S. E. F., Transcript profiling of expressed sequence tags from semimembranosus muscle of commercial and naturalized pig breeds, vol. 11, pp. 3315-3328, 2012.
Bai Q, McGillivray C, da CN, Dornan S, et al. (2003). Development of a porcine skeletal muscle cDNA microarray: analysis of differential transcript expression in phenotypically distinct muscles. BMC Genomics 4: 8. http://dx.doi.org/10.1186/1471-2164-4-8 PMid:12611633 PMCid:152649   Brandt U (2006). Energy converting NADH:quinone oxidoreductase (complex I). Annu. Rev. Biochem. 75: 69-92. http://dx.doi.org/10.1146/annurev.biochem.75.103004.142539 PMid:16756485   Briggs HM and Briggs DM (1969). In Modern Breeds of Livestock. The MacMillan Co., New York.   Conesa A, Gotz S, Garcia-Gomez JM, Terol J, et al. (2005). Blast2GO: a universal tool for annotation, visualization and analysis in functional genomics research. Bioinformatics 21: 3674-3676. http://dx.doi.org/10.1093/bioinformatics/bti610 PMid:16081474   Davoli R, Zambonelli P, Bigi D, Fontanesi L, et al. (1999). Analysis of expressed sequence tags of porcine skeletal muscle. Gene 233: 181-188. http://dx.doi.org/10.1016/S0378-1119(99)00141-9   Davoli R, Fontanesi L, Zambonelli P, Bigi D, et al. (2002). Isolation of porcine expressed sequence tags for the construction of a first genomic transcript map of the skeletal muscle in pig. Anim. Genet. 33: 3-18. http://dx.doi.org/10.1046/j.1365-2052.2002.00800.x PMid:11849132   Ewing B, Hillier L, Wendl MC and Green P (1998). Base-calling of automated sequencer traces using phred. I. Accuracy assessment. Genome Res. 8: 175-185. PMid:9521921   Ferraz AL, Ojeda A, Lopez-Bejar M, Fernandes LT, et al. (2008). Transcriptome architecture across tissues in the pig. BMC Genomics 9: 173. http://dx.doi.org/10.1186/1471-2164-9-173 PMid:18416811 PMCid:2335121   Guimarães SEF and Lopes OS (2001). Uso de recursos genéticos nativos no mapeamento genético de suínos. Ação Ambiental 15: 27-28.   Hocquette JF, Ortigues-Marty I and Pethick D (1998). Nutritional and hormonal regulation of energy metabolism in skeletal muscles of meat-producing animals. Livest. Prod. Sci. 56: 115-143. http://dx.doi.org/10.1016/S0301-6226(98)00187-0   Huang X and Madan A (1999). CAP3: A DNA sequence assembly program. Genome Res. 9: 868-877. http://dx.doi.org/10.1101/gr.9.9.868 PMid:10508846 PMCid:310812   Kim NK, Lim JH and Song MJ (2008). Comparisons of longissimus muscle metabolic enzymes and muscle fibre types in Korean and western pig breeds. Meat Sci. 78: 455-460. http://dx.doi.org/10.1016/j.meatsci.2007.07.014 PMid:22062465   Lin CS and Hsu CW (2005). Differentially transcribed genes in skeletal muscle of Duroc and Taoyuan pigs. J. Anim. Sci. 83: 2075-2086. PMid:16100062   Lopes PS, Guimarães SEF, Pires AV, Soares MAM, et al. (2002). Performance, Carcass Yield and Meat Quality Traits of F2 Crosses Between Brazilian Native and Commercial Pigs for QTL Mapping. Proceedings in World Congresss on Genetics Applied to Livestock Production: Montpellier, 155-158.   Mégy K, Audic S and Claverie JM (2002). Heart-specific genes revealed by expressed sequence tag (EST) sampling. Genome Biol. 3: RESEARCH0074.   Min XJ, Butler G, Storms R and Tsang A (2005). TargetIdentifier: a webserver for identifying full-length cDNAs from EST sequences. Nucleic Acids Res. 33: W669-W672. http://dx.doi.org/10.1093/nar/gki436 PMid:15980559 PMCid:1160197   Nobis W, Ren X, Suchyta SP, Suchyta TR, et al. (2003). Development of a porcine brain cDNA library, EST database, and microarray resource. Physiol. Genomics 16: 153-159. http://dx.doi.org/10.1152/physiolgenomics.00099.2003 PMid:14559975   Rehfeldt C, Henning M and Fiedler I (2008). Consequences of pig domestication for skeletal muscle growth and cellularity. Livest. Sci. 116: 30-41. http://dx.doi.org/10.1016/j.livsci.2007.08.017   Sambrook J and Russell DW (2001). Molecular Cloning. A Laboratory Manual. Cold Spring Harbor Press, Cold Spring Harbor.   Serão NV, Veroneze R, Ribeiro AM, Verardo LL, et al. (2011). Candidate gene expression and intramuscular fat content in pigs. J. Anim. Breed. Genet. 128: 28-34. http://dx.doi.org/10.1111/j.1439-0388.2010.00887.x PMid:21214641   Souza CA, Paiva SR, Pereira RW, Guimaraes SE, et al. (2009). Iberian origin of Brazilian local pig breeds based on Cytochrome b (MT-CYB) sequence. Anim. Genet. 40: 759-762. http://dx.doi.org/10.1111/j.1365-2052.2009.01899.x PMid:19422368   Tang Z, Li Y, Wan P, Li X, et al. (2007). LongSAGE analysis of skeletal muscle at three prenatal stages in Tongcheng and Landrace pigs. Genome Biol. 8: R115. http://dx.doi.org/10.1186/gb-2007-8-6-r115 PMid:17573972 PMCid:2394763   Vianna AT (1985). Os Suínos. 14ª ed. Editora Nobel, São Paulo.   Wang XL, Wu KL, Li N, Li CL, et al. (2006). Analysis of expressed sequence tags from skeletal muscle-specific cDNA library of Chinese native Xiang pig. Yi Chuan Xue Bao 33: 984-991. PMid:17112969   Wimmers K, Ngu NT, Jennen DG, Tesfaye D, et al. (2008). Relationship between myosin heavy chain isoform expression and muscling in several diverse pig breeds. J. Anim. Sci. 86: 795-803. http://dx.doi.org/10.2527/jas.2006-521 PMid:18156349   Wu J, Zhou D, Deng C, Wu X, et al. (2008). Characterization of porcine ENO3: genomic and cDNA structure, polymorphism and expression. Genet. Sel. Evol. 40: 563-579. PMid:18694551 PMCid:2674891
2011
I. Fonseca, Antunes, G. R., Paiva, D. S., Lange, C. C., Guimarães, S. E. F., and Martins, M. F., Differential expression of genes during mastitis in Holstein-Zebu crossbreed dairy cows, vol. 10, pp. 1295-1303, 2011.
Alluwaimi AM, Leutenegger CM, Farver TB, Rossitto PV, et al. (2003). The cytokine markers in Staphylococcus aureus mastitis of bovine mammary gland. J. Vet. Med. B. Infect. Dis. Vet. Public Health 50: 105-111. doi:10.1046/j.1439-0450.2003.00628.x Bannerman DD, Paape MJ, Lee JW, Zhao X, et al. (2004a). Escherichia coli and Staphylococcus aureus elicit differential innate immune responses following intramammary infection. Clin. Diagn. Lab. Immunol. 11: 463-472. PMid:15138171    PMCid:404560 Bannerman DD, Paape MJ, Hare WR and Hope JC (2004b). Characterization of the bovine innate immune response to intramammary infection with Klebsiella pneumoniae. J. Dairy Sci. 87: 2420-2432. doi:10.3168/jds.S0022-0302(04)73365-2 Bannerman DD, Chockalingam A, Paape MJ and Hope JC (2005). The bovine innate immune response during experimentally-induced Pseudomonas aeruginosa mastitis. Vet. Immunol. Immunopathol. 107: 201-215. doi:10.1016/j.vetimm.2005.04.012 PMid:15970335 Bannerman DD, Rinaldi M, Vinyard BT, Laihia J, et al. (2009). Effects of intramammary infusion of cis-urocanic acid on mastitis-associated inflammation and tissue injury in dairy cows. Am. J. Vet. Res. 70: 373-382. doi:10.2460/ajvr.70.3.373 PMid:19254150 Bradley A (2002). Bovine mastitis: an evolving disease. Vet. J. 164: 116-128. doi:10.1053/tvjl.2002.0724 PMid:12359466 Burvenich C, Van M, V, Mehrzad J, Diez-Fraile A, et al. (2003). Severity of E. coli mastitis is mainly determined by cow factors. Vet. Res. 34: 521-564. doi:10.1051/vetres:2003023 PMid:14556694 Cates EA, Connor EE, Mosser DM and Bannerman DD (2009). Functional characterization of bovine TIRAP and MyD88 in mediating bacterial lipopolysaccharide-induced endothelial NF-kappaB activation and apoptosis. Comp. Immunol. Microbiol. Infect. 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Induction of type 2 cytokines by a staphylococcal enterotoxin superantigen. J. Nat. Toxins. 7: 193-213. PMid:9783259 Fonseca I, Silva PV, Lange CC and Guimarães MFM (2009). Expression profile of genes associated with mastitis in dairy cattle. Genet. Mol. Biol. 32: 776-781. doi:10.1590/S1415-47572009005000074 PMid:21637453    PMCid:3036910 Goldammer T, Zerbe H, Molenaar A, Schuberth HJ, et al. (2004). Mastitis increases mammary mRNA abundance of beta-defensin 5, toll-like-receptor 2 (TLR2), and TLR4 but not TLR9 in cattle. Clin. Diagn. Lab. Immunol. 11: 174-185. PMid:14715566    PMCid:321333 Griesbeck-Zilch B, Meyer HH, Kuhn CH, Schwerin M, et al. (2008). Staphylococcus aureus and Escherichia coli cause deviating expression profiles of cytokines and lactoferrin messenger ribonucleic acid in mammary epithelial cells. J. Dairy Sci. 91: 2215-2224. doi:10.3168/jds.2007-0752 PMid:18487644 Hirschfeld M, Ma Y, Weis JH, Vogel SN, et al. (2000). 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