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Found 11 results
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2013
J. R. Pesarini, Zaninetti, P. T., Mauro, M. O., Carreira, C. M., Dichi, J. B., Ribeiro, L. R., Mantovani, M. S., and Oliveira, R. J., Antimutagenic and anticarcinogenic effects of wheat bran in vivo, vol. 12, pp. 1646-1659, 2013.
M. O. Mauro, Monreal, M. T. F. D., Silva, M. T. P., Pesarini, J. R., Mantovani, M. S., Ribeiro, L. R., Dichi, J. B., Carreira, C. M., and Oliveira, R. J., Evaluation of the antimutagenic and anticarcinogenic effects of inulin in vivo, vol. 12, pp. 2281-2293, 2013.
A. M. Niwa, Oliveira, R. J., and Mantovani, M. S., Evaluation of the mutagenicity and antimutagenicity of soy phytoestrogens using micronucleus and comet assays of the peripheral blood of mice, vol. 12, pp. 519-527, 2013.
Adlercreutz H, Mazur W, Bartels P, Elomaa V, et al. (2000). Phytoestrogens and prostate disease. J. Nutr. 130: 658S-659S. PMid:10702603   Bedani R and Rossi EA (2005). Isoflavonas: bioquímica, fisiologia e implicações para a saúde. B CEPPA 23: 231-264.   Boersma BJ, Barnes S, Kirk M, Wang CC, et al. (2001). Soy isoflavonoids and cancer - metabolism at the target site. Mutat. Res. 480-481: 121-127. http://dx.doi.org/10.1016/S0027-5107(01)00175-0   Di Virgilio AL, Iwami K, Watjen W, Kahl R, et al. (2004). Genotoxicity of the isoflavones genistein, daidzein and equol in V79 cells. Toxicol. Lett. 151: 151-162. http://dx.doi.org/10.1016/j.toxlet.2004.04.005 PMid:15177650   Djuric Z, Chen G, Doerge DR, Heilbrun LK, et al. (2001). Effect of soy isoflavone supplementation on markers of oxidative stress in men and women. Cancer Lett. 172: 1-6. http://dx.doi.org/10.1016/S0304-3835(01)00627-9   Ebert MN, Beyer-Sehlmeyer G, Liegibel UM, Kautenburger T, et al. (2001). Butyrate induces glutathione S-transferase in human colon cells and protects from genetic damage by 4-hydroxy-2-nonenal. Nutr. Cancer 41: 156-164. PMid:12094619   Esteves EA and Monteiro JBR (2001). Efeitos benéficos das isoflavonas de soja em doenças crônicas. Rev. Nutr. 14: 43-52. http://dx.doi.org/10.1590/S1415-52732001000100007   Fenech M (2000). The in vitro micronucleus technique. Mutat. Res. 455: 81-95. http://dx.doi.org/10.1016/S0027-5107(00)00065-8   Ferguson LR, Philpott M and Karunasinghe N (2004). Dietary cancer and prevention using antimutagens. Toxicology 198: 147-159. http://dx.doi.org/10.1016/j.tox.2004.01.035 PMid:15138038   Ferrari RA and Demiate IM (2001). Isoflavonas de soja: uma breve revisão. Publicativo UEPG: Biol. Health Sci. 7: 39-46.   Fotakis G and Timbrell JA (2006). In vitro cytotoxicity assays: comparison of LDH, neutral red, MTT and protein assay in hepatoma cell lines following exposure to cadmium chloride. Toxicol. Lett. 160: 171-177. http://dx.doi.org/10.1016/j.toxlet.2005.07.001 PMid:16111842   Gontijo AMMC and Tice R (2003). Teste do Cometa para a Detecção de Dano no DNA e Reparo em Células Individualizadas. In: Mutagênese Ambiental (Ribeiro LR, Salvadori DMF and Marques EK, eds.). Ulbra, Canoas, 247-271.   Hayashi M, Morita T, Kodama Y, Sofuni T, et al. (1990). The micronucleus assay with mouse peripheral blood reticulocytes using acridine orange-coated slides. Mutat. Res. 245: 245-249. http://dx.doi.org/10.1016/0165-7992(90)90153-B   Izumi T, Piskula MK, Osawa S, Obata A, et al. (2000). Soy isoflavone aglycones are absorbed faster and in higher amounts than their glucosides in humans. J. Nutr. 130: 1695-1699. PMid:10867038   Klein CB and King AA (2007). Genistein genotoxicity: critical considerations of in vitro exposure dose. Toxicol. Appl. Pharmacol. 224: 1-11. http://dx.doi.org/10.1016/j.taap.2007.06.022 PMid:17688899   Kulling SE, Lehmann L and Metzler M (2002). Oxidative metabolism and genotoxic potential of major isoflavone phytoestrogens. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 777: 211-218. http://dx.doi.org/10.1016/S1570-0232(02)00215-5   Mendes J (2008). Modulação do Efeito Mutagênico por Fitoestrógeno in vitro e in vivo. Master's thesis, UEL, Londrina.   Mendes J, Tsuboy MS, Marcarini JC, Hoffmann-Campo CB, et al. (2012). Modulation of the mutagenic effect of benzo[a] pyrene and bleomycin by isoflavone extracts in a rat hepatome cell line. Semina: Ciênc. Biol. Saúde 33: 11-20.   Michael MR, Wolz E, Davidovich A and Bausch J (2006). Genetic toxicity studies with genistein. Food Chem. Toxicol. 44: 42-55. http://dx.doi.org/10.1016/j.fct.2005.06.004 PMid:16198038   Moon YJ, Wang X and Morris ME (2006). Dietary flavonoids: effects on xenobiotic and carcinogen metabolism. Toxicol. In Vitro 20: 187-210. http://dx.doi.org/10.1016/j.tiv.2005.06.048 PMid:16289744   Peterson G and Barnes S (1991). Genistein inhibition of the growth of human breast cancer cells: independence from estrogen receptors and the multi-drug resistance gene. Biochem. Biophys. Res. Commun. 179: 661-667. http://dx.doi.org/10.1016/0006-291X(91)91423-A   Pool-Zobel B, Veeriah S and Bohmer FD (2005). Modulation of xenobiotic metabolising enzymes by anticarcinogens -- focus on glutathione S-transferases and their role as targets of dietary chemoprevention in colorectal carcinogenesis. Mutat. Res. 591: 74-92. http://dx.doi.org/10.1016/j.mrfmmm.2005.04.020 PMid:16083918   Ribeiro LR and Salvadori DM (2003). Dietary components may prevent mutation-related diseases in humans. Mutat. Res. 544: 195-201. http://dx.doi.org/10.1016/j.mrrev.2003.06.019 PMid:14644321   Setchell KD (2000). Absorption and metabolism of soy isoflavones-from food to dietary supplements and adults to infants. J. Nutr. 130: 654S-655S. PMid:10702601   Singh NP, McCoy MT, Tice RR and Schneider EL (1988). A simple technique for quantitation of low levels of DNA damage in individual cells. Exp. Cell Res. 175: 184-191. http://dx.doi.org/10.1016/0014-4827(88)90265-0   Stopper H, Schmitt E and Kobras K (2005). Genotoxicity of phytoestrogens. Mutat. Res. 574: 139-155. http://dx.doi.org/10.1016/j.mrfmmm.2005.01.029 PMid:15914213
I. Aquino, Tsuboy, M. S. F., Marcarini, J. C., Mantovani, M. S., Perazzo, F. F., and Maistro, E. L., Genotoxic evaluation of the antimalarial drugs artemisinin and artesunate in human HepG2 cells and effects on CASP3 and SOD1 gene expressions, vol. 12, pp. 2517-2527, 2013.
R. J. Oliveira, Sassaki, E. S., Monreal, A. C. D., Monreal, M. T. F. D., Pesarini, J. R., Mauro, M. O., Matuo, R., Silva, A. F., Zobiole, N. N., Siqueira, J. M., Ribeiro, L. R., and Mantovani, M. S., Pre-treatment with glutamine reduces genetic damage due to cancer treatment with cisplatin, vol. 12, pp. 6040-6051, 2013.
2011
E. L. Maistro, Angeli, J. P. F., Andrade, S. F., and Mantovani, M. S., In vitro genotoxicity assessment of caffeic, cinnamic and ferulic acids, vol. 10, pp. 1130-1140, 2011.
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Novel and therapeutic effect of caffeic acid and caffeic acid phenyl ester on hepatocarcinoma cells: complete regression of hepatoma growth and metastasis by dual mechanism. FASEB J. 18: 1670-1681. doi:10.1096/fj.04-2126com PMid:15522912 Eastmond DA and Tucker JD (1989). Identification of aneuploidy-inducing agents using cytokinesis-blocked human lymphocytes and an antikinetochore antibody. Environ. Mol. Mutagen. 13: 34-43. doi:10.1002/em.2850130104 PMid:2783409 Ferguson LR (2001). Role of plant polyphenols in genomic stability. Mutat. Res. 475: 89-111. doi:10.1016/S0027-5107(01)00073-2 Ferguson LR, van Zijl P, Holloway WD and Jones WT (1985). Condensed tannins induce micronuclei in cultured V79 1139 ©FUNPEC-RP www.funpecrp.com.br Genetics and Molecular Research 10 (2): 1130-1140 (2011) Genotoxicity assessment of caffeic, cinnamic and ferulic acids Chinese hamster cells. Mutat. Res. 158: 89-95. Fulcher RG (1983). Fluorescence Microscopy of Cereals. 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Mutat. Res. 116: 333-339. doi:10.1016/0165-1218(83)90071-X Hirose M, Takesada Y, Tanaka H, Tamano S, et al. (1997). Carcinogenicity of antioxidants BHA, caffeic acid, sesamol, 4-methoxyphenol and catechol at low doses, either alone or in combination, and modulation of their effects in a rat médium-term multi-organ carcinogenesis model. Carcinogenesis 19: 207-212. doi:10.1093/carcin/19.1.207 PMid:9472713 Kanski J, Aksenova M, Stoyanova A and Butterfield DA (2002). Ferulic acid antioxidant protection against hydroxyl and peroxyl radical oxidation in synaptosomal and neuronal cell culture systems in vitro: structure-activity studies. J. Nutr. Biochem. 13: 273-281. doi:10.1016/S0955-2863(01)00215-7 Kawabata K, Yamamoto T, Hara A, Shimizu M, et al. (2000). Modifying effects of ferulic acid on azoxymethane-induced colon carcinogenesis in F344 rats. Cancer Lett. 157: 15-21. doi:10.1016/S0304-3835(00)00461-4 Kobayashi H, Sugiyama C, Morikawa Y, Hayashi M, et al. (1995). A comparison between the manual microscopic analisys and computerized image analisys in the single cell gel electrophoresis. MMS Commun. 3: 103-115. Kuroda Y, Yoo YS and Ishibashi T (1984). Antimutagenic activity of food additives. Mutat. Res. 130: 369. Lesca P (1983). Protective effects of ellagic acid and other plant phenols on benzo[a]pyrene-induced neoplasia in mice. Carcinogenesis 4: 1651-1653. doi:10.1093/carcin/4.12.1651 PMid:6317220 Lijinsky W and Andrews AW (1980). Mutagenicity of vinyl compounds in Salmonella typhimurium. Teratog. Carcinog. Mutagen. 1: 259-267. doi:10.1002/tcm.1770010303 Mosmann T (1983). Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods 65: 55-63. doi:10.1016/0022-1759(83)90303-4 Munari CC, Alves JM, Bastos JK and Tavares DC (2010). Evaluation of the genotoxic and antigenotoxic potential of Baccharis dracunculifolia extract on V79 cells by the comet assay. J. Appl. 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The comet assay: a sensitive genotoxicity test for the detection of DNA damage. Methods Mol. Biol. 291: 85-95. PMid:15502214 Sri BM, Rukkumani R and Menon VP (2003). Protective effects of ferulic acid on hyperlipidemic diabetic rats. Acta Diabetol. 40: 118-122. doi:10.1007/s00592-003-0099-6 PMid:14605967 Srinivasan M, Sudheer AR and Menon VP (2007). Ferulic acid: therapeutic potential through its antioxidant property. J. Clin. Biochem. Nutr. 40: 92-100. doi:10.3164/jcbn.40.92 PMid:18188410    PMCid:2127228 Tavares DC, Mazzaron Barcelos GR, Silva LF, Chacon Tonin CC, et al. (2006). Propolis-induced genotoxicity and antigenotoxicity in Chinese hamster ovary cells. Toxicol. In Vitro 20: 1154-1158. doi:10.1016/j.tiv.2006.02.009 PMid:16682170 Tice RR, Agurell E, Anderson D, Burlinson B, et al. (2000). Single cell gel/comet assay: guidelines for in vitro and in vivo genetic toxicology testing. Environ. Mol. 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