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X. L. Liu, Ren, J. K., and Su, Y. L., Association between IL-4 gene polymorphisms, IL-4 serum levels, and ankylosing spondylitis, vol. 15, no. 4, p. -, 2016.
Conflicts of interestThe authors declare no conflict of interest.REFERENCESBanchereau J, et al (2015). Generation of human B-cell lines dependent on CD40-ligation and interleukin-4. Front. Immunol. 6: 55. Baysal O, Durmuş B, Ersoy Y, Altay Z, et al (2011). Relationship between psychological status and disease activity and quality of life in ankylosing spondylitis. Rheumatol. Int. 31: 795-800. Bellini A, Marini MA, Bianchetti L, Barczyk M, et al (2012). Interleukin (IL)-4, IL-13, and IL-17A differentially affect the profibrotic and proinflammatory functions of fibrocytes from asthmatic patients. Mucosal Immunol. 5: 140-149. Boonen A, Braun J, van der Horst Bruinsma IE, Huang F, et al (2010). ASAS/WHO ICF Core Sets for ankylosing spondylitis (AS): how to classify the impact of AS on functioning and health. Ann. Rheum. Dis. 69: 102-107. Burton OT, Darling AR, Zhou JS, Noval-Rivas M, et al (2013). 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Cortes A, Hadler J, Pointon JP, Robinson PC, International Genetics of Ankylosing Spondylitis Consortium (IGAS)Australo-Anglo-American Spondyloarthritis Consortium (TASC)Groupe Française d’Etude Génétique des Spondylarthrites (GFEGS)Nord-Trøndelag Health Study (HUNT)Spondyloarthritis Research Consortium of Canada (SPARCC)Wellcome Trust Case Control Consortium 2 (WTCCC2)et al (2013). Identification of multiple risk variants for ankylosing spondylitis through high-density genotyping of immune-related loci. Nat. Genet. 45: 730-738. Jenkins SJ, Ruckerl D, Thomas GD, Hewitson JP, et al (2013). IL-4 directly signals tissue-resident macrophages to proliferate beyond homeostatic levels controlled by CSF-1. J. Exp. Med. 210: 2477-2491. Jin GX, Duan JZ, Guo WL, Li L, et al (2013). Association between IL-1RN gene polymorphisms and susceptibility to ankylosing spondylitis: a large Human Genome Epidemiology review and meta-analysis. Genet. Mol. Res. 12: 1720-1730. 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The association between tumor necrosis factor alpha promoter polymorphisms and ankylosing spondylitis: a meta-analysis. Hum. Immunol. 74: 1357-1362. Noack M, Miossec P, et al (2014). Th17 and regulatory T cell balance in autoimmune and inflammatory diseases. Autoimmun. Rev. 13: 668-677. Spiess C, Bevers J3rdJackmanJ, Chiang N, et al (2013). Development of a human IgG4 bispecific antibody for dual targeting of interleukin-4 (IL-4) and interleukin-13 (IL-13) cytokines. J. Biol. Chem. 288: 26583-26593. Suzuki A, Leland P, Joshi BH, Puri RK, et al (2015). Targeting of IL-4 and IL-13 receptors for cancer therapy. Cytokine 75: 79-88. Toellner KM, et al (2014). Cognate interactions: extrafollicular IL-4 drives germinal-center reactions, a new role for an old cytokine. Eur. J. Immunol. 44: 1917-1920. van der Heijde D, Zack D, Wajdula J, Sridharan S, et al (2014). Rates of serious infections, opportunistic infections, inflammatory bowel disease, and malignancies in subjects receiving etanercept vs. controls from clinical trials in ankylosing spondylitis: a pooled analysis. Scand. J. Rheumatol. 43: 49-53. Vijayanand P, Seumois G, Simpson LJ, Abdul-Wajid S, et al (2012). Interleukin-4 production by follicular helper T cells requires the conserved Il4 enhancer hypersensitivity site V. Immunity 36: 175-187. Wallis SK, Cooney LA, Endres JL, Lee MJ, et al (2011). A polymorphism in the interleukin-4 receptor affects the ability of interleukin-4 to regulate Th17 cells: a possible immunoregulatory mechanism for genetic control of the severity of rheumatoid arthritis. Arthritis Res. Ther. 13: R15. Wang C, Liao Q, Hu Y, Zhong D, et al (2015). T lymphocyte subset imbalances in patients contribute to ankylosing spondylitis. Exp. Ther. Med. 9: 250-256. Wang CM, Ho HH, Chang SW, Wu YJ, et al (2012). ERAP1 genetic variations associated with HLA-B27 interaction and disease severity of syndesmophytes formation in Taiwanese ankylosing spondylitis. Arthritis Res. Ther. 14: R125. Zhang L, Li YG, Li YH, Qi L, et al (2012). Increased frequencies of Th22 cells as well as Th17 cells in the peripheral blood of patients with ankylosing spondylitis and rheumatoid arthritis. PLoS One 7: e31000. Zhang L, Huang Y, Liu Z, Liu W, et al (2015). Dynamics of T-cell subsets and their relationship with oral and systemic opportunistic infections in HIV/AIDS patients during the first year of HAART in Guangxi, China. J. Med. Virol. 87: 1158-1167.  
N. Long, Liu, N., Liu, X. L., Li, J., Cai, B. Y., Cai, X., Long, N., Liu, N., Liu, X. L., Li, J., Cai, B. Y., and Cai, X., Endometrial expression of telomerase, progesterone, and estrogen receptors during the implantation window in patients with recurrent implantation failure, vol. 15, p. -, 2016.
N. Long, Liu, N., Liu, X. L., Li, J., Cai, B. Y., Cai, X., Long, N., Liu, N., Liu, X. L., Li, J., Cai, B. Y., and Cai, X., Endometrial expression of telomerase, progesterone, and estrogen receptors during the implantation window in patients with recurrent implantation failure, vol. 15, p. -, 2016.
Y. Liu, Liu, X. L., He, H., and Gu, Y. L., Four SNPs of insulin-induced gene 1 associated with growth and carcass traits in Qinchuan cattle in China, vol. 11, pp. 1209-1216, 2012.
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