Publications

Aliaga JC, Deschenes C, Beaulieu JF, Calvo EL, et al. (1999). Requirement of the MAP kinase cascade for cell cycle progression and differentiation of human intestinal cells. Am. J. Physiol. 277: G631-G641. PMid:10484389   Bueno OF and Molkentin JD (2002). Involvement of extracellular signal-regulated kinases 1/2 in cardiac hypertrophy and cell death. Circ. Res. 91: 776-781. http://dx.doi.org/10.1161/01.RES.0000038488.38975.1A PMid:12411391   Cho HS, Chang SH, Chung YS, Shin JY, et al. (2009). Synergistic effect of ERK inhibition on tetrandrine-induced apoptosis in A549 human lung carcinoma cells. J. Vet. Sci. 10: 23-28. http://dx.doi.org/10.4142/jvs.2009.10.1.23 PMid:19255520 PMCid:2801106   Garrington TP and Johnson GL (1999). Organization and regulation of mitogen-activated protein kinase signaling pathways. Curr. Opin. Cell Biol. 11: 211-218. http://dx.doi.org/10.1016/S0955-0674(99)80028-3   Hajjar RJ and Samulski RJ (2006). Heart failure: a silver bullet to treat heart failure. Gene Ther. 13: 997. http://dx.doi.org/10.1038/sj.gt.3302747 PMid:17262904   Hausenloy DJ, Tsang A and Yellon DM (2005). The reperfusion injury salvage kinase pathway: a common target for both ischemic preconditioning and postconditioning. Trends Cardiovasc. Med. 15: 69-75. http://dx.doi.org/10.1016/j.tcm.2005.03.001 PMid:15885573   Kuno Y, Kondo K, Iwata H, Senga T, et al. (1998). Tumor-specific activation of mitogen-activated protein kinase in human colorectal and gastric carcinoma tissues. Jpn. J. Cancer Res. 89: 903-909. http://dx.doi.org/10.1111/j.1349-7006.1998.tb00647.x PMid:9818025   Lemieux E, Bergeron S, Durand V, Asselin C, et al. (2009). Constitutively active MEK1 is sufficient to induce epithelial-to-mesenchymal transition in intestinal epithelial cells and to promote tumor invasion and metastasis. Int. J. Cancer 125: 1575-1586. http://dx.doi.org/10.1002/ijc.24485 PMid:19462441   Li DY, Tao L, Liu H, Christopher TA, et al. (2006). Role of ERK1/2 in the anti-apoptotic and cardioprotective effects of nitric oxide after myocardial ischemia and reperfusion. Apoptosis 11: 923-930. http://dx.doi.org/10.1007/s10495-006-6305-6 PMid:16547595   Li XM, Ma YT, Yang YN, Liu F, et al. (2009). Downregulation of survival signalling pathways and increased apoptosis in the transition of pressure overload-induced cardiac hypertrophy to heart failure. Clin. Exp. Pharmacol. Physiol. 36: 1054-1061. http://dx.doi.org/10.1111/j.1440-1681.2009.05243.x PMid:19566828   Licato LL and Brenner DA (1998). Analysis of signaling protein kinases in human colon or colorectal carcinomas. Dig. Dis. Sci. 43: 1454-1464. http://dx.doi.org/10.1023/A:1018894227169 PMid:9690379   Lips DJ, Bueno OF, Wilkins BJ, Purcell NH, et al. (2004). MEK1-ERK2 signaling pathway protects myocardium from ischemic injury in vivo. Circulation 109: 1938-1941. http://dx.doi.org/10.1161/01.CIR.0000127126.73759.23 PMid:15096454   Manning G, Whyte DB, Martinez R, Hunter T, et al. (2002). The protein kinase complement of the human genome. Science 298: 1912-1934. http://dx.doi.org/10.1126/science.1075762 PMid:12471243   Mebratu Y and Tesfaigzi Y (2009). How ERK1/2 activation controls cell proliferation and cell death: Is subcellular localization the answer? Cell Cycle 8: 1168-1175. http://dx.doi.org/10.4161/cc.8.8.8147 PMid:19282669 PMCid:2728430   Pacak CA, Mah CS, Thattaliyath BD, Conlon TJ, et al. (2006). Recombinant adeno-associated virus serotype 9 leads to preferential cardiac transduction in vivo. Circ. Res. 99: e3-e9. http://dx.doi.org/10.1161/01.RES.0000237661.18885.f6 PMid:16873720   Prasad KM, Xu Y, Yang Z, Acton ST, et al. (2011). Robust cardiomyocyte-specific gene expression following systemic injection of AAV: in vivo gene delivery follows a Poisson distribution. Gene Ther. 18: 43-52. http://dx.doi.org/10.1038/gt.2010.105 PMid:20703310 PMCid:2988989   Simpson P and Savion S (1982). Differentiation of rat myocytes in single cell cultures with and without proliferating nonmyocardial cells. Cross-striations, ultrastructure, and chronotropic response to isoproterenol. Circ. Res. 50: 101- 116. http://dx.doi.org/10.1161/01.RES.50.1.101 PMid:7053872   Treisman R (1996). Regulation of transcription by MAP kinase cascades. Curr. Opin. Cell Biol. 8: 205-215. http://dx.doi.org/10.1016/S0955-0674(96)80067-6   Voisin L, Julien C, Duhamel S, Gopalbhai K, et al. (2008). Activation of MEK1 or MEK2 isoform is sufficient to fully transform intestinal epithelial cells and induce the formation of metastatic tumors. BMC Cancer 8: 337. http://dx.doi.org/10.1186/1471-2407-8-337 PMid:19014680 PMCid:2596176   White JD, Thesier DM, Swain JB, Katz MG, et al. (2011). Myocardial gene delivery using molecular cardiac surgery with recombinant adeno-associated virus vectors in vivo. Gene Ther. 18: 546-552. http://dx.doi.org/10.1038/gt.2010.168 PMid:21228882   Yue TL, Wang C, Gu JL, Ma XL, et al. (2000). Inhibition of extracellular signal-regulated kinase enhances Ischemia/ Reoxygenation-induced apoptosis in cultured cardiac myocytes and exaggerates reperfusion injury in isolated perfused heart. Circ. Res. 86: 692-699. http://dx.doi.org/10.1161/01.RES.86.6.692 PMid:10747006