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“Extract from mistletoe, Viscum album L., reduces Hsp27 and 14-3-3 protein expression and induces apoptosis in C6 rat glioma cells”, vol. 11, pp. 2801-2813, 2012.
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Aitken A (2006). 14-3-3 proteins: a historic overview. Semin. Cancer Biol. 16: 162-172.
http://dx.doi.org/10.1016/j.semcancer.2006.03.005
PMid:16678438
Andrieu C, Taieb D, Baylot V, Ettinger S, et al. (2010). Heat shock protein 27 confers resistance to androgen ablation and chemotherapy in prostate cancer cells through eIF4E. Oncogene 29: 1883-1896.
http://dx.doi.org/10.1038/onc.2009.479
PMid:20101233
Arrigo AP (2007). Anti-Apoptotic, Tumorigenic and Metastatic Potential of Hsp27 (HspB1) and aB-crystallin (HspB5): Emerging Targets for the Development of New Anti-Cancer Therapeutic Strategies. In: Heat Shock Proteins in Cancer (Calderwood SK, Sherman MY and Ciocca DR, eds.). Springer, New York, 73-92.
http://dx.doi.org/10.1007/978-1-4020-6401-2_4
PMid:16906400
Büssing A and Schietzel M (1999). Apoptosis-inducing properties of Viscum album L. extracts from different host trees, correlate with their content of toxic mistletoe lectins. Anticancer Res. 19: 23-28.
PMid:10226520
Cao L, Cao W, Zhang W, Lin H, et al. (2008). Identification of 14-3-3 protein isoforms in human astrocytoma by immunohistochemistry. Neurosci. Lett. 432: 94-99.
http://dx.doi.org/10.1016/j.neulet.2007.11.071
PMid:18242847
Cao WD, Zhang X, Zhang JN, Yang ZJ, et al. (2006). Immunocytochemical detection of 14-3-3 in primary nervous system tumors. J. Neurooncol. 77: 125-130.
http://dx.doi.org/10.1007/s11060-005-9027-7
PMid:16292484
Chen XL, Zhou L, Yang J, Shen FK, et al. (2010). Hepatocellular carcinoma-associated protein markers investigated by MALDI-TOF MS. Mol. Med. Rep. 3: 589-596.
http://dx.doi.org/10.3892/mmr_00000302
PMid:21472284
Ciocca DR and Calderwood SK (2005). Heat shock proteins in cancer: diagnostic, prognostic, predictive, and treatment implications. Cell Stress Chaperones 10: 86-103.
http://dx.doi.org/10.1379/CSC-99r.1
PMid:16038406 PMCid:1176476
Cipak L, Novotny L, Cipakova I and Rauko P (2003). Differential modulation of cisplatin and doxorubicin efficacies in leukemia cells by flavonoids. Nutr. Res. 23: 1045-1057.
http://dx.doi.org/10.1016/S0271-5317(03)00078-2
Didelot C, Lanneau D, Brunet M, Joly AL, et al. (2007). Anti-cancer therapeutic approaches based on intracellular and extracellular heat shock proteins. Curr. Med. Chem. 14: 2839-2847.
http://dx.doi.org/10.2174/092986707782360079
PMid:18045130
Ernst E, Schmidt K and Steuer-Vogt MK (2003). Mistletoe for cancer? A systematic review of randomised clinical trials. Int. J. Cancer 107: 262-267.
http://dx.doi.org/10.1002/ijc.11386
PMid:12949804
Garrido C, Brunet M, Didelot C, Zermati Y, et al. (2006). Heat shock proteins 27 and 70: anti-apoptotic proteins with tumorigenic properties. Cell Cycle 5: 2592-2601.
http://dx.doi.org/10.4161/cc.5.22.3448
PMid:17106261
Gorman AM, Heavey B, Creagh E, Cotter TG, et al. (1999). Antioxidant-mediated inhibition of the heat shock response leads to apoptosis. FEBS Lett. 445: 98-102.
http://dx.doi.org/10.1016/S0014-5793(99)00094-0
Graner MW and Bigner DD (2005). Chaperone proteins and brain tumors: potential targets and possible therapeutics. Neuro Oncol. 7: 260-278.
http://dx.doi.org/10.1215/S1152851704001188
PMid:16053701 PMCid:1871914
Hamad I, Erol-Dayi O, Pekmez M, Önay-Uçar E, et al. (2010). Antioxidant and cytotoxic activities of Aphanes arvensis extracts. Plant Foods Hum. Nutr. 65: 44-49.
http://dx.doi.org/10.1007/s11130-009-0151-y
PMid:20108047
Harwood M, Danielewska-Nikiel B, Borzelleca JF, Flamm GW, et al. (2007). A critical review of the data related to the safety of quercetin and lack of evidence of in vivo toxicity, including lack of genotoxic/carcinogenic properties. Food Chem. Toxicol. 45: 2179-2205.
http://dx.doi.org/10.1016/j.fct.2007.05.015
PMid:17698276
Hermeking H (2003). The 14-3-3 cancer connection. Nat. Rev. Cancer 3: 931-943.
http://dx.doi.org/10.1038/nrc1230
PMid:14737123
Jakubowicz-Gil J, Rzymowska J and Gawron A (2002). Quercetin, apoptosis, heat shock. Biochem. Pharmacol. 64: 1591- 1595.
http://dx.doi.org/10.1016/S0006-2952(02)01356-4
Jakubowicz-Gil J, Paduch R, Piersiak T, Glowniak K, et al. (2005). The effect of quercetin on pro-apoptotic activity of cisplatin in HeLa cells. Biochem. Pharmacol. 69: 1343-1350.
http://dx.doi.org/10.1016/j.bcp.2005.01.022
PMid:15826605
Kamada M, So A, Muramaki M, Rocchi P, et al. (2007). Hsp27 knockdown using nucleotide-based therapies inhibit tumor growth and enhance chemotherapy in human bladder cancer cells. Mol. Cancer Ther. 6: 299-308.
http://dx.doi.org/10.1158/1535-7163.MCT-06-0417
PMid:17218637
Karagöz A, Onay E, Arda N and Kuru A (2003). Antiviral potency of mistletoe (Viscum album ssp. album) extracts against human parainfluenza virus type 2 in Vero cells. Phytother. Res. 17: 560-562.
http://dx.doi.org/10.1002/ptr.1163
PMid:12749000
Li Z, Zhao J, Du Y, Park HR, et al. (2008). Down-regulation of 14-3-3zeta suppresses anchorage-independent growth of lung cancer cells through anoikis activation. Proc. Natl. Acad. Sci. U. S. A. 105: 162-167.
http://dx.doi.org/10.1073/pnas.0710905105
PMid:18162532 PMCid:2224179
Li Z, Dong Z, Myer D, Yip-Schneider M, et al. (2010). Role of 14-3-3σ in poor prognosis and in radiation and drug resistance of human pancreatic cancers. BMC Cancer 10: 598.
http://dx.doi.org/10.1186/1471-2407-10-598
PMid:21040574 PMCid:2991307
Liang P and MacRae TH (1997). Molecular chaperones and the cytoskeleton. J. Cell Sci. 110: 1431-1440.
PMid:9224761
Liang S, Shen G, Liu Q, Xu Y, et al. (2009). Isoform-specific expression and characterization of 14-3-3 proteins in human glioma tissues discovered by stable isotope labeling with amino acids in cell culture-based proteomic analysis. Proteomics Clin. Appl. 3: 743-753.
http://dx.doi.org/10.1002/prca.200800198
PMid:21136983
Martin H, Patel Y, Jones D, Howell S, et al. (1993). Antibodies against the major brain isoforms of 14-3-3 protein. An antibody specific for the N-acetylated amino-terminus of a protein. FEBS Lett. 331: 296-303.
http://dx.doi.org/10.1016/0014-5793(93)80356-Y
Önay-Uçar E, Karagöz A and Arda N (2006). Antioxidant activity of Viscum album ssp. album. Fitoterapia 77: 556-560.
http://dx.doi.org/10.1016/j.fitote.2006.08.001
PMid:17056203
Parcellier A, Brunet M, Schmitt E, Col E, et al. (2006). HSP27 favors ubiquitination and proteasomal degradation of p27Kip1 and helps S-phase re-entry in stressed cells. FASEB J. 20: 1179-1181.
http://dx.doi.org/10.1096/fj.05-4184fje
PMid:16641199
Rocchi P, Jugpal P, So A, Sinneman S, et al. (2006). Small interference RNA targeting heat-shock protein 27 inhibits the growth of prostatic cell lines and induces apoptosis via caspase-3 activation in vitro. BJU Int. 98: 1082-1089.
http://dx.doi.org/10.1111/j.1464-410X.2006.06425.x
PMid:16879439
Seit-Nebi AS and Gusev NB (2010). Versatility of the small heat shock protein HSPB6 (Hsp20). Cell Stress Chaperones 15: 233-236.
http://dx.doi.org/10.1007/s12192-009-0141-x
PMid:19777375 PMCid:2866997
van Hemert MJ, Steensma HY and van Heusden GP (2001). 14-3-3 proteins: key regulators of cell division, signalling and apoptosis. BioEssays 23: 936-946.
http://dx.doi.org/10.1002/bies.1134
PMid:11598960
Yano M, Nakamuta S, Wu X, Okumura Y, et al. (2006). A novel function of 14-3-3 protein: 14-3-3z is a heat-shock-related molecular chaperone that dissolves thermal-aggregated proteins. Mol. Biol. Cell 17: 4769-4779.
http://dx.doi.org/10.1091/mbc.E06-03-0229
PMid:16943323 PMCid:1635386
Zarkovic N, Vukovic T, Loncaric I, Miletic M, et al. (2001). An overview on anticancer activities of the Viscum album extract Isorel. Cancer Biother. Radiopharm. 16: 55-62.
http://dx.doi.org/10.1089/108497801750096041
PMid:11279798
Zhang R, Tremblay TL, McDermid A, Thibault P, et al. (2003). Identification of differentially expressed proteins in human glioblastoma cell lines and tumors. Glia 42: 194-208.
http://dx.doi.org/10.1002/glia.10222
PMid:12655603
Zhang WL, Tsuneishi S and Nakamura H (2001). Induction of heat shock proteins and its effects on glial differentiation in rat C6 glioblastoma cells. Kobe J. Med. Sci. 47: 77-95.
PMid:11599126
Zhu Z, Xu X, Yu Y, Graham M, et al. (2010). Silencing heat shock protein 27 decreases metastatic behavior of human head and neck squamous cell cancer cells in vitro. Mol. Pharmacol. 7: 1283-1290.
http://dx.doi.org/10.1021/mp100073s
PMid:20540527 PMCid:2914182