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“Sodium valproate inhibits MDA-MB-231 breast cancer cell migration by upregulating NM23H1 expression”, vol. 11, pp. 77-86, 2012.
, Adams LS, Phung S, Yee N, Seeram NP, et al. (2010). Blueberry phytochemicals inhibit growth and metastatic potential of MDA-MB-231 breast cancer cells through modulation of the phosphatidylinositol 3-kinase pathway. Cancer Res. 70: 3594-3605.
http://dx.doi.org/10.1158/0008-5472.CAN-09-3565
PMid:20388778 PMCid:2862148
Baneshi MR, Warner P, Anderson N, Edwards J, et al. (2010). Tamoxifen resistance in early breast cancer: statistical modelling of tissue markers to improve risk prediction. Br. J. Cancer 102: 1503-1510.
http://dx.doi.org/10.1038/sj.bjc.6605627
PMid:20461093 PMCid:2869158
Blaheta RA, Nau H, Michaelis M and Cinatl J Jr (2002). Valproate and valproate-analogues: potent tools to fight against cancer. Curr. Med. Chem. 9: 1417-1433.
PMid:12173980
Byun SS, Kim FJ, Khandrika L, Kumar B, et al. (2009). Differential effects of valproic acid on growth, proliferation and metastasis in HTB5 and HTB9 bladder cancer cell lines. Cancer Lett. 281: 196-202.
http://dx.doi.org/10.1016/j.canlet.2009.02.045
PMid:19324494
Chen PS, Wang CC, Bortner CD, Peng GS, et al. (2007). Valproic acid and other histone deacetylase inhibitors induce microglial apoptosis and attenuate lipopolysaccharide-induced dopaminergic neurotoxicity. Neuroscience 149: 203- 212.
http://dx.doi.org/10.1016/j.neuroscience.2007.06.053
PMid:17850978 PMCid:2741413
D’Angelo A, Garzia L, Andre A, Carotenuto P, et al. (2004). Prune cAMP phosphodiesterase binds nm23-H1 and promotes cancer metastasis. Cancer Cell 5: 137-149.
http://dx.doi.org/10.1016/S1535-6108(04)00021-2
D’Souza A, Onem E, Patel P, La Gamma EF, et al. (2009). Valproic acid regulates catecholaminergic pathways by concentration-dependent threshold effects on TH mRNA synthesis and degradation. Brain Res. 1247: 1-10.
http://dx.doi.org/10.1016/j.brainres.2008.09.088
PMid:18976638
Dragunow M, Greenwood JM, Cameron RE, Narayan PJ, et al. (2006). Valproic acid induces caspase 3-mediated apoptosis in microglial cells. Neuroscience 140: 1149-1156.
http://dx.doi.org/10.1016/j.neuroscience.2006.02.065
PMid:16600518
Duenas-Gonzalez A, Candelaria M, Perez-Plascencia C, Perez-Cardenas E, et al. (2008). Valproic acid as epigenetic cancer drug: preclinical, clinical and transcriptional effects on solid tumors. Cancer Treat. Rev. 34: 206-222.
http://dx.doi.org/10.1016/j.ctrv.2007.11.003
PMid:18226465
Dutertre M, Gratadou L, Dardenne E, Germann S, et al. (2010). Estrogen regulation and physiopathologic significance of alternative promoters in breast cancer. Cancer Res. 70: 3760-3770.
http://dx.doi.org/10.1158/0008-5472.CAN-09-3988
PMid:20406972
Fortunati N, Bertino S, Costantino L, Bosco O, et al. (2008). Valproic acid is a selective antiproliferative agent in estrogen-sensitive breast cancer cells. Cancer Lett. 259: 156-164.
http://dx.doi.org/10.1016/j.canlet.2007.10.006
PMid:18006146
Jawed S, Kim B, Ottenhof T, Brown GM, et al. (2007). Human melatonin MT1 receptor induction by valproic acid and its effects in combination with melatonin on MCF-7 breast cancer cell proliferation. Eur. J. Pharmacol. 560: 17-22.
http://dx.doi.org/10.1016/j.ejphar.2007.01.022
PMid:17303109
Jin L, Liu G, Zhang CH, Lu CH, et al. (2009). Nm23-H1 regulates the proliferation and differentiation of the human chronic myeloid leukemia K562 cell line: a functional proteomics study. Life Sci. 84: 458-467.
http://dx.doi.org/10.1016/j.lfs.2009.01.010
PMid:19302816
Lagneaux L, Gillet N, Stamatopoulos B, Delforge A, et al. (2007). Valproic acid induces apoptosis in chronic lymphocytic leukemia cells through activation of the death receptor pathway and potentiates TRAIL response. Exp. Hematol. 35: 1527-1537.
http://dx.doi.org/10.1016/j.exphem.2007.06.014
PMid:17697742
Leone A, McBride OW, Weston A, Wang MG, et al. (1991). Somatic allelic deletion of nm23 in human cancer. Cancer Res. 51: 2490-2493.
PMid:2015608
Liang M, Zhang P and Fu J (2007). Up-regulation of LOX-1 expression by TNF-alpha promotes trans-endothelial migration of MDA-MB-231 breast cancer cells. Cancer Lett. 258: 31-37.
http://dx.doi.org/10.1016/j.canlet.2007.08.003
PMid:17868983
Marshall SF, Clarke CA, Deapen D, Henderson K, et al. (2010). Recent breast cancer incidence trends according to hormone therapy use: the California Teachers Study cohort. Breast Cancer Res. 2: R4.
http://dx.doi.org/10.1186/bcr2467
PMid:20064209 PMCid:2880422
Platta CS, Greenblatt DY, Kunnimalaiyaan M and Chen H (2008). Valproic acid induces Notch1 signaling in small cell lung cancer cells. J Surg. Res. 148: 31-37.
http://dx.doi.org/10.1016/j.jss.2008.03.008
PMid:18570928 PMCid:2900385
Shen WT, Wong TS, Chung WY, Wong MG, et al. (2005). Valproic acid inhibits growth, induces apoptosis, and modulates apoptosis-regulatory and differentiation gene expression in human thyroid cancer cells. Surgery 138: 979-984.
http://dx.doi.org/10.1016/j.surg.2005.09.019
PMid:16360381
Swain SM, Jeong JH, Geyer CE Jr, Costantino JP, et al. (2010). Longer therapy, iatrogenic amenorrhea, and survival in early breast cancer. N. Engl. J. Med. 362: 2053-2065.
http://dx.doi.org/10.1056/NEJMoa0909638
PMid:20519679 PMCid:2935316
Wu L, Li Z, Zhang Y, Zhang P, et al. (2008). Adenovirus-expressed human hyperpla- sia suppressor gene induces apoptosis in cancer cells. Mol. Cancer Ther. 7: 222-232.
http://dx.doi.org/10.1158/1535-7163.MCT-07-0382
PMid:18202024