Brief Note

Related GMR Articles

07/31/2015
Meta-analysis; Polymorphism; Pulmonary tuberculosis; Tumor necrosis factor

The aim of this study was to determine whether tumor necrosis factor-α (TNF-α) polymorphisms are associated with susceptibility to pulmonary tuberculosis (PTB) in different ethnic populations. MEDLINE and Embase databases and manual searches were employed to identify articles in which TNF-α polymorphisms were determined in patients with PTB and controls ... more

Y.H. Lee; G.G. Song
07/28/2015
Gastric cancer; Meta-analysis; MicroRNA; Polymorphism

Gastric cancer (GC) is a prevalent disease with a high mortality rate, especially in developing countries. Accumulating evidence suggests that single nucleotide polymorphisms in microRNA (miRNA) genes might influence the susceptibility to GC; such sequence variation might contribute to the development of disease by altering crucial cellular pathways. In this study, we assessed the ... more

Y.P. Gu; Q.Y. Yuan; H. Zhang; C.J. Wang; F. Zhou
07/28/2015
Hepatitis B virus; MIF-173G/C; Polymorphism

In addition to the host immune response, genetic and environmental factors play crucial roles in the manifestation of hepatitis B virus (HBV) infection. The macrophage migration inhibitory factor (MIF) -173G/C polymorphism (rs755622), located in the promoter region of MIF, may play integral roles in diverse processes, including the immune response. Thus, the MIF -173G/C ... more

Z.S. Wang; C.C. Yin; S. Han; F.L. Jiang; W.G. Guo; L.Q. Wu; S.H. Liu
07/28/2015
Interleukin-17; Polymorphism; Pulmonary tuberculosis

We conducted a case-control study in a Chinese population to examine the correlations between interleukin (IL)-17 gene polymorphisms and tuberculosis (TB) development. The study population included 336 TB subjects and 351 control subjects who were enrolled between June 2012 and June 2014. Genotyping analyses of IL-17A rs2275913 and rs3748067 and IL-17F rs763780 were analyzed using ... more

G.C. Shi; L.G. Zhang
07/17/2015
Breeding; Germplasm bank; Pepper; Polymorphism; Simple sequence repeat

In order to support further genetic, diversity, and phy­logeny studies of Capsicum species, the transferability of a Capsicum annuum L. simple sequence repeat (SSR) microsatellite set was ana­lyzed for C. frutescens L. (“malagueta” and “tabasco” peppers) and C. chinense Jacq. (smell peppers, among other types). A total of 185 SSR primers were evaluated ... more

S.I.C. Carvalho; C.F. Ragassi; I.B. Oliveira; Z.P.S. Amaral; F.J.B. Reifschneider; F.G. Faleiro; G.S.C. Buso
07/13/2015
hsa-miR-146a; Intracranial aneurysm; Polymorphism; susceptibility

Vascular inflammation has been shown to be involved in the pathogenesis of intracranial aneurysms (IA). MiRNAs are key molecules that participate in the regulation of many important biological processes including inflammation. Studies on the hsa-miR-146a rs2910164 polymorphism and its association with different inflammatory related diseases have engendered inconsistent ... more

X.T. Sima; J.G. Xu; J. Li; C. You
07/13/2015
Insulin-like growth factors; Osteoporosis; Polymorphism

We conducted a case-control study to assess the relation­ship between rs35767, rs2288377, and rs5742612 insulin-like growth factor-1 (IGF-1) and osteoporosis risk in a Chinese female population. The genotypes of rs35767, rs2288377, and rs5742612 of IGF-1 were determined by polymerase chain reaction-restriction fragment length polymorphism. Patients with osteoporosis were more likely to ... more

W. Zhang; L.C. Zhang; H. Chen; P.F. Tang; L.H. Zhang
07/13/2015
Polymorphism; Renal cell carcinomas; Vascular endothelial growth factor

We conducted a case-control study in a Chinese population to assess whether 5 common single-nucleotide polymor­phisms in the vascular endothelial growth factor gene (VEGF) affect the risk of renal cell carcinoma (RCC). The study population in­cluded 266 RCC patients who were newly diagnosed and histologi­cally confirmed to have RCC as well as 532 cancer-free controls. Genotyping ... more

W. Xian; H. Zheng; W.J. Wu
12/29/2015
Meta-analysis; Polymorphism; Prostate cancer

Recent studies have indicated that single nucleotide polymorphisms (SNPs) within the 8q24 region may be a risk factor for prostate cancer (PCa). Here, we performed a meta-analysis to evaluate the association between the 8q24 rs6983267 T/G polymorphism and PCa risk. A systematic literature search was carried out in multiple electronic databases independently by two investigators. Pooled ... more

H.S. Zhu; J.F. Zhang; J.D. Zhou; M.J. Zhang; H.X. Hu
12/29/2015
Early-onset preeclampsia; Interleukin-10; Polymorphism

In this case-control study, we assessed the influence of IL-10 -1082A/G and -819T/C on the development of preeclampsia. The IL-10 -1082A/G and -819T/C polymorphisms were assessed by polymerase chain reaction-restriction fragment length polymorphism. The genotype distributions of the IL-10 -1082A/G and -819T/C polymorphisms in the control subjects were in ... more

Q.Y. Liu; F.Y. Gao; X.R. Liu; J. Li; M. Ji; J. Dong; X.T. Wang

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