Brief Note

Related GMR Articles

Chinese population; Gastric cancer; IL-17; Polymorphism

We conducted a study to investigate the role of three IL-17 gene single nucleotide polymorphisms (SNP) (rs2275913G>A, rs3748067C>T, and rs763780 T>C) in the development of gastric cancer. A total of 252 patients with gastric cancer and 252 control subjects were collected between May 2012 and May 2014. The SNP genotyping of IL-17A rs2275913G>A and rs3748067C ... more

W.T. Qi; J.L. Gao; S.S. Zhang
Polymorphism; Retinal vein occlusion; RVO; Thrombophilia

In this study, we assessed the prevalence of polymorphisms in genes involved in hyperhomocysteinemia or hemostasis to shed light on their role, if any, in retinal vein occlusion (RVO). We recruited 37 Italian patients (17 men and 20 women) with a diagnosis of central or branch RVO based on fundus examination and retinal fluorescein angiography, as well as 45 healthy controls. Risk ... more

L. De Polo; P.E. Maltese; E. Rigoni; M. Bertelli; S. Cecchin; G. Staurenghi; G. Stoppa
Chronic obstructive pulmonary disease; Polymorphism; Proteinase-activated receptor-1

We conducted a case-control study to investigate the association between PAR1 gene polymorphisms and the development of chronic obstructive pulmonary disease (COPD). A total of 270 patients with COPD and 270 control subjects were consecutively recruited between March 2012 and March 2014. A polymerase chain reaction restriction fragment length polymorphism assay was used to assess ... more

C.M. Yun; X.Y. Sang
A-20C; Angiotensinogen gene; Essential hypertension; Meta-analysis; Polymorphism

The A-20C polymorphism in the angiotensinogen (AGT) gene has been associated with increased risk of essential hypertension in several studies; however, these studies gave inconsistent results. In this study, we performed a meta-analysis to assess the association between AGT A-20C polymorphism and essential hypertension. Published literature was retrieved from PubMed. ... more

R. Zeng; Q.P. Wang; M.X. Fang; J. Zhuang; R.X. Fan
Censured data; Mixed model; Polymorphism

The aim of this study was to compare genomic selection methodologies using a linear mixed model and the Cox survival model. We used data from an F2 population of pigs, in which the response variable was the time in days from birth to the culling of the animal and the covariates were 238 markers [237 single nucleotide polymorphism (SNP) plus the halothane gene]. The data were corrected ... more

V.S. Santos; M. Filho; M.D.V. Resende; C.F. Azevedo; P.S. Lopes; S.E.F. Guimarães; L.S. Glória; F.F. Silva
Coronary artery disease; Interleukin gene; Polymorphism

We conducted a case-control study to investigate the genetic variants Interleukin-1β(IL-1β) +3953 C/T (rs1143634), IL-6 -174G/C (rs1800795), IL-8 -251T/A (rs4073), and IL-10 -1082A/G (rs1800896) and -819C/T (rs1800871) in the development of coronary artery disease (CAD). A total of 410 individuals with CAD were ... more

H.T. Yang; S.L. Wang; L.J. Yan; P. Qian; H.Y. Duan
Chloroplast microsatellite; Gossypium; Polymorphism; Transferability

Cotton is an important economic crop worldwide; its fiber, commonly known as cotton lint, is the main natural source for the textile industry. Sixty chloroplast microsatellites were identified and characterized from the complete sequence of the Gossypium hirsutum chloroplast genome using a bioinformatic approach. Twenty chloroplast microsatellite loci were polymorphic in the 66 ... more

X.Y. Cai; F. Liu; Z.L. Zhou; X.X. Wang; C.Y. Wang; Y.H. Wang; K.B. Wang
APOA5 -1131T/C; Coronary artery disease; Meta-analysis; Polymorphism

Although many studies have investigated the association of the APOA5 -1131T/C polymorphism with coronary artery disease (CAD), definite conclusions have not been drawn. To understand the effects of the APOA5 -1131T/C polymorphism on the risk of developing CAD, we performed an updated meta-analysis in the Chinese population. Relevant studies published till April 2015 were identified from ... more

J. Zhang; D.G. Wan; H.L. Song; W.G. Zhang
CCDC26; Glioma; Meta-analysis; Polymorphism; rs4295627

The association between the CCDC26 rs4295627 single nucleotide polymorphism (SNP) and the glioma risk has been studied previously, but these studies have yielded conflicting results. The aim of the present study is to analyze this association more vigorously, by means of a meta-analysis. A comprehensive literature search was performed in databases PubMed and EMBASE. Six articles ... more

H.W. Lu; M. Huang; J.H. Wang; X.L. Sun; Y.Q. Ke