Brief Note

Related GMR Articles

10/05/2015
CCDC26; Glioma; Meta-analysis; Polymorphism; rs4295627

The association between the CCDC26 rs4295627 single nucleotide polymorphism (SNP) and the glioma risk has been studied previously, but these studies have yielded conflicting results. The aim of the present study is to analyze this association more vigorously, by means of a meta-analysis. A comprehensive literature search was performed in databases PubMed and EMBASE. Six articles ... more

H.W. Lu; M. Huang; J.H. Wang; X.L. Sun; Y.Q. Ke
10/05/2015
Interleukin factors; Myocardial infarction; Polymorphism

Myocardial infarction (MI) is currently a leading cause of death worldwide, and is caused by various environmental and genetic factors. We therefore conducted a case-control study to investigate the association between polymorphisms in interleukins IL-1β, IL-8, and IL-10 and MI risk. This study recruited 260 MI patients and 285 control subjects. Genotyping of IL-1β +3954C/T, IL-8 -251T/A, ... more

S. Wang; Y.X. Dai; L.L. Chen; T. Jiang; M.Q. Zheng; C.G. Li; Y.P. Chen; W.H. Lin; J.F. Zhang; J. Jiang
10/05/2016
ADH1B; ALDH2; Alzheimer’s disease; Polymorphism

In the present study, we investigated the association between ADH1B rs1229984 and ALDH2 rs671 polymorphisms and the development of Alzheimer’s disease in a Chinese population. Genotyping of the ADH1B rs1229984 and ALDH2 rs671 polymorphisms was carried out by polymerase chain reaction-restriction fragment length polymorphism. Logistic regression analyses ... more

L. Ma; Z.N. Lu; L. Ma; Z.N. Lu
11/03/2016
Alpha-actinin 3; Angiotensin-converting enzyme; Muscle fiber; Polymorphism; Scoliosis

The etiology of adolescent idiopathic scoliosis remains unknown. Angiotensin-converting enzyme and α-actinin-3 polymorphisms influence the characteristics of muscle fibers. The aim of this study was to examine the association between idiopathic scoliosis and genetic polymorphism of angiotensin-converting enzyme and α-actinin-3. Ninety-seven females with scoliosis, ... more

R.P. Luciano; M. Wajchenberg; S.S. Almeida; C.E.N. Amorim; L.M.R. Rodrigues; R.C. Araujo; E.B. Puertas; F. Faloppa; R.P. Luciano; M. Wajchenberg; S.S. Almeida; C.E.N. Amorim; L.M.R. Rodrigues; R.C. Araujo; E.B. Puertas; F. Faloppa
11/21/2016
IL-8; Meta-analysis; Periodontitis; Polymorphism

The -251A/T polymorphism in the anti-inflammatory cytokine interleukin-8 (IL-8) gene has been implicated in susceptibility to periodontitis; however, this correlation has not been elucidated. In this meta-analysis, we investigated the association between the IL-8 -251A/T polymorphism and the risk of periodontitis. All eligible case-control studies ... more

Z.J. Yang; X.P. Tang; Q.G. Lai; J.B. Ci; K.F. Yuan; Z.J. Yang; X.P. Tang; Q.G. Lai; J.B. Ci; K.F. Yuan; Z.J. Yang; X.P. Tang; Q.G. Lai; J.B. Ci; K.F. Yuan
11/25/2016
ABCB1; ABCC2; Antiepileptic drugs; Polymorphism

Epilepsy is a common disease of the nervous system; approximately 20-30% of all patients with epilepsy are reported resistant to antiepileptic drugs. ABCB1 and ABCC2 are members of ATP-binding cassette transporter (ABC) family that is involved in the excretion of antiepileptic drugs. In this case-control study, we have investigated the ... more

T. Xue; Z.N. Lu
10/21/2017
IGF2BP2; Polymorphism; Vitiligo

Vitiligo is a disorder of pigmentation presenting with loss of melanocytes in the epidermis and hair follicles. The gene for insulin-like growth factor binding protein 2 (IGF2BP2) is located on the third chromosome and it plays role in growth, development, cellular differentiation, and metabolism. In the present study, we aimed to investigate the rs1470579 and ... more

K. Kargun; B. Demir; D. Cicek; O.Sevil Karstarli
11/29/2017
ADH; ALDH; Lymph node metastasis; Oral cancer; Polymorphism
Oral cancer incidence is higher in individuals between
the fifth and seventh decades of life, but some studies indicate a
decreasing age trend. From the epidemiological point of view,
alcohol consumption is associated with the emergence of oral cancer
by interfering with mechanisms of DNA synthesis and repair. From
a genetic standpoint, ... more
J.T. Takamori; M. Santos; G.T. Peterle; L. Rossi; O.A. Curioni; D. Gazito; L.L. Maia; I.D. Louro; M.M. de Oliveira; J.G. dos Santos; R.A. Moyses; P.M. Cury; T.N. Toporcov; J.L. Kanda; A.M.A. da Silva; M.B. de Carvalho
11/29/2017
Correlation; Polymorphism; PRND; PRNP alleles
The interaction between the ovine prion protein gene
(PRNP) and Doppel (PRND) gene polymorphisms is essential for
understanding the role of prion proteins in scrapie. In this study, the
blood genomic DNA samples of 111 Gansu Alpine Merino sheep
were used to define the PRNP alleles and the haplotypes of PRND
by PCR-SSCP (single-strand ... more
Yzi Liu; Clin Zhao; Y.Ze Yang; R. Wu; C. Wang; X.Rui Wan; Y. Wang
05/05/2018
Microsatellite loci; Polymorphism; Sebastes schlegelii

Twenty-three polymorphic microsatellite loci were developed from the black rockfish, Sebastes schlegelii, with an enriched partial genomic library by magnetic beads and polymorphism of these loci was assessed in 32 individuals from a wild population. The loci yielded 2-19 alleles per locus, the observed, expected heterozygosity and polymorphic information content ... more

F. Wang; H.B.Jiang C. H.; H.G. P; C.C.F. Jia; H.T. Ma

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