Research Article

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05/10/2011
Bioinformatic analysis; Heat shock protein 70; HSP70; Immune response; Mycoplasma ovipneumoniae; Recombinant protein

Mycoplasma ovipneumoniae, a bacterial species that specifically affects ovine and goat, is the cause of ovine infectious pleuropneumonia. We cloned, sequenced and analyzed heat shock protein 70 (HSP70) (dnaK) gene of M. ovipneumoniae. The full length open reading frame of the M. ovipneumoniae HSP70 gene consists of 1812 nucleotides, with a G+C content of 34.16%, ... more

M. Li; C.J. Ma; X.M. Liu; D. Zhao; Q.C. Xu; Y.J. Wang
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Glutamine synthetase; Immune response; Messenger RNA expression; Tegillarca granosa; Vibrio parahaemolyticus

The blood cockle, Tegillarca granosa, is a widely consumed clam in the Indo-Pacific region. Glutamine synthetase (GS) is an enzyme that plays an essential role in the metabolism of nitrogen by catalyzing the condensation of glutamate and ammonia to form glutamine. We identified the GS of T. granosa (Tg-GS) from hemocytes by 3'- and 5'-rapid amplification of cDNA ends ( ... more

Y.B. Bao; L. Li; M.X. Ye; Y.H. Dong; W.X. Jin; Z.H. Lin
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Cisplatin; Immune response; Lactobacillus; Lung cancer

The intestinal microflora affects inflammation and immunity, not only locally at the mucosal level but also systemically, raising the question of whether the microflora affects inflammatory processes that contribute to cancer and its therapy. Prebiotics have also been found to play an antitumor role that is not limited to the gut. We investigated the antitumor roles of the intestinal ... more

Q.F. Gui; H.F. Lu; C.X. Zhang; Z.R. Xu; Y.H. Yang
04/10/2015
Ammonia concentration; broiler; Immune response; Relative humidity

To investigate the effect of ammonia (NH3) and humidity on the immune response of broilers, broilers were exposed to 30 or 70 mg/kg atmospheric NH3 for 21 days. Additionally, birds were exposed to 35, 60, and 85% relative humidity (RH). The relative weights of lymphoid organs, serum total protein, serum globulin, serum albumin, serum lysozyme, proliferation index of ... more

F.X. Wei; X.F. Hu; B. Xu; M.H. Zhang; S.Y. Li; Q.Y. Sun; P. Lin
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Immune response; Pearl oyster; Pinctada martensii; Purple acid phosphatase

Purple acid phosphatases (PAPs), also known as type 5 acid phosphatases, are widely present in animals, plants, and fungi. In mammal, PAP was reported to participate in immune defense and bone resorption. In this study, the characteristics and potential functions of a PAP gene from pearl oyster Pinctada martensii (pm-PAP) were examined. The Pm-PAP cDNA was found to be 2777 base ... more

Q.H. Wang; Y. Jiao; X.D. Du; X.X. Zhao; R.L. Huang; Y.W. Deng; F. Yan
06/30/2007
Electrophoretic profile; Hemoglobin polymorphism; Hemoglobins; Rhinoclemmys punctularia

Studies of the hemoglobin pattern in Brazilian reptiles are important for determining ecological and phylogenetic relationships, but they are scarce. Peripheral blood samples were obtained from 7 males and 18 females of Rhinoclemmys punctularia. The hematological profile was based on the total hemoglobin and hematocrit values. The hemoglobin profile was obtained using electrophoretic ... more

C.R. Bonini-Domingos; M.B. Silva; R.M. Romero; P.J.A. Zamaro; L.S. Ondei; C.E.S. Zago; S.B. Moreira; C.G. Salgado
6/29/2017
Adolescent; Adult; Anemia, Sickle Cell; Child; Child, Preschool; Female; Gene Deletion; Haplotypes; Hemoglobins; Humans; male; Middle Aged; Polymorphism, Genetic; Receptors, CCR5

Sickle cell disease shows several clinical manifestations in distinct levels of severity. This heterogeneity is due to the haplotype variability associated with the HbS gene, levels of fetal hemoglobin and environmental conditions, which modify the disease expression. Science community believes that the presence of a polymorphism in the CCR5 gene, which is related to chronic inflammatory state ... more

A.F. Nascimento; J.S. Oliveira; J.C.Silva Junior; A.A.L. Barbosa
06/28/2006
1; 3-b-glucan synthase; Gene structure; Intron evolution; Paracoccidioides brasiliensis

The evolutionary origin and significance of spliceosomal introns have been the subject of many investigations. Two theories, “introns-early” theory and “introns-late” theory, have been proposed to explain the evolution of introns in eukaryotic genes. Intron position is generally conserved in paralogue and orthologue genes. Some introns occur at similar but not necessarily identical positions ... more

M. Pereira; H.T.S. Okamoto; C.M.A. Soares
03/30/2015
Gene expression; Gene structure; Nilaparvata lugens; NlABCG; Tissue distribution

The ATP-binding cassette (ABC) transporters belong to a large superfamily of proteins that have important physiological functions in all living organisms. In insects, ABC transporters have important functions in the transport of molecules, and are also involved in insecticide resistance, metabolism, and development. In this study, the Nilaparvata lugens Stal (Hemiptera: ... more

W.J. Zha; S.H. Li; L. Zhou; Z.J. Chen; K. Liu; G.C. Yang; G. Hu; G.C. He; A.Q. You
07/05/2011
Immune response; Real-time PCR; Resistance to mastitis; Toll-like receptor 2 gene

Among the potential public health problems of animal production, infectious-contagious diseases stand out. Mastitis is among the main diseases affecting dairy cattle. One of the most promising options to reduce the problems caused by this disease, besides proper sanitary and management practices, is selective breeding of resistant animals. To shed light on the immune response mechanisms ... more

I. Fonseca; G.R. Antunes; D.S. Paiva; C.C. Lange; S.E.F. Guimarães; M.F. Martins

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