Research Article

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09/27/2011
eNOS; Essential hypertension; Han population; Haplotype; SNPs

Endothelial nitric oxide synthase (eNOS) plays an important role in maintaining blood pressure homeostasis and vascular integrity. Polymorphisms in the eNOS gene have been found to be associated with hypertension in different human populations, including Northern and Southern Chinese Han populations. To examine the relationship of three eNOS gene polymorphisms, T-786C ( ... more

J. Li; Y. Cun; W.R. Tang; Y. Wang; S.N. Li; H.R. Ouyang; Y.R. Wu; H.J. Yu; C.J. Xiao
04/14/2014
Camellia sinensis; Expressed sequence tag; Haplotype; Nucleotide diversity; Single nucleotide polymorphisms

Tea is the second most popular non-alcoholic beverage in the world. In recent years, several molecular markers have been used in genetic studies of the tea plant. Yet, only a few single nucleotide polymorphisms (SNPs) have been reported. Here, we identified 818 putative SNPs from expressed sequence tag (EST) databases for the tea plant, which produced a frequency of 1 SNP/170 bp. A ... more

C.C. Zhang; L.Y. Wang; K. Wei; H. Cheng
04/29/2014
Chicken; FADS2; Fatty acid; Growth traits; Haplotype; Single nucleotide polymorphisms

Delta-6 fatty acid desaturases are rate-limiting desaturases involved in metabolic processes of fatty acids, and they are encoded by the FADS2 gene. In the current study, an F2 resource population of Gushi chickens crossed with Anak broilers was used to investigate the genetic effects of the chicken FADS2. Two adjacent single nucleotide polymorphisms (SNPs) ( ... more

S.K. Zhu; Y.D. Tian; S. Zhang; Q.X. Chen; Q.Y. Wang; R.L. Han; X.T. Kang
06/11/2015
Genetic polymorphism; Genotype; Haplotype; Killer cell immunoglobulin-like receptor (KIR); Polymerase chain reaction-sequence specific primers

The aim of this study was to explore the genetic polymorphism, genotype, and haplotype characteristics of the KIR locus in the Xinjiang Han population in order to establish a foundation for future analysis of the relationship between KIR genes and disease. KIR genes were detected by sequence-specific primer-polymerase chain reaction in 184 randomly selected, ... more

G.Y. Lin; B. Yu; W.J. Hu; Y.Z. Zhang; X.J. Zuo; Y.B. Wang
04/27/2015
Cleaved amplified polymorphic sequence (CAPS); endo-PG gene; Haplotype; Insertion/deletions (indels); Single nucleotide polymorphism

Single nucleotide polymorphisms (SNPs) are the most abundant sequence variations found in plant genomes and are widely used as molecular genetic markers in genetic diversity studies and crossbreeding programs. In this study, we examined 113 DNA sequences of the endopolygalacturonase (endo-PG) gene from 67 peach accessions and found a total of 56 SNPs and 6 insertion/deletions ( ... more

Y. Jiao; R. Ma; M. Yu
08/03/2010
DNA; DYS464; Microsatellites; Population genetics; Worldwide populations; Y-chromosome

Of all DNA markers on the human Y-chromosome, the tetra-local Y-linked microsatellite DYS464 is the most polymorphic. We genotyped DYS464 in 677 male samples collected worldwide, maintained in the HGDP-CEPH Human Genome Diversity Cell Line Panel. Fourteen different alleles were found, with allele lengths varying from 9 to 23 repeats. One hundred and seventy-five ... more

F.S.G. Kehdy; S.D.J. Pena
03/18/2008
Allele frequencies; Bolivian population; DNA typing; Forensic science; Population genetics; Short tandem repeat

Two hundred and sixty unrelated subjects who asked for paternity testing at two Bolivian Laboratories in La Paz and Santa Cruz were studied. The loci D3S1358, vWA, FGA, D8S1179, D21S11, D18S51, D5S818, D13S317, D7S820, TH01, TPOX, and CSF1PO were typed from blood samples, amplifying DNA by polymerase chain reactions and electrophoresis. Allele frequencies were estimated by simple counting and ... more

L. Cifuentes; H. Jorquera; M. Acuña; J. Ordóñez; A.L. Sierra
04/25/2014
Cervidae; Huemul; Nonspecific microsatellites; Pudu; Short tandem repeat; Species genetic determination

Thirty-nine microsatellite loci that are highly conserved in red deer, sika deer, reindeer, Soay sheep, and other artiodactyls were tested in two vulnerable and endangered Neotropical deer (pudu: Pudu puda and huemul: Hippocamelus bisulcus) with the aim of producing a standardized set of markers that can be used successfully in noninvasive samples from these species. We ... more

J.C. Marín; P. Orozco-terWengel; K. Romero; J.P. Vásquez; V. Varas; J.A. Vianna

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