Research Article

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02/03/2012
Children; Han; Henoch-Schonlein purpura; HLA-A; HLA-B; Mongolian

We examined a possible association between HLA-A and -B polymorphisms and susceptibility to Henoch-Schönlein purpura (HSP) in Han and Mongolian children in Inner Mongolia, through a case-control study. Two hundred and sixty-eight unrelated children were enrolled, including 56 Mongolian and 50 Han children with HSP, 66 healthy Mongolian and 96 healthy Han children as a control group. HLA-A ... more

S.M. Ren; G.L. Yang; C.Z. Liu; C.X. Zhang; Q.H. Shou; S.F. Yu; W.C. Li; X.L. Su
12/18/2014
Children; Cytokine profile; Hemopathy; infection; Phase of bone marrow inhibition

Serum cytokine profiles were analyzed before and after infection in children with hemopathy in the bone marrow inhibition phase to explore the utility of cytokine variations for detecting infections. Serum Th1/Th2 cytokine levels, including tumor necrosis factor, interleukin (IL)-2, IL-4, IL-6, IL-10, and interferon, were quantitatively determined by cytometric bead array technology in ... more

X.D. Chen; B. Chen; Y.M. Tang; H. Song; S.W. Shi; S.L. Yang; W.Q. Xu; B.H. Pan; F.Y. Zhao; N. Zhao; L.Y. Zhang; J.Q. Mao
06/09/2014
Children; Disease classification; High resolution CT; Interstitial lung disease

High resolution computed tomography (HRCT) was used to classify children with interstitial lung diseases (ILD). Sixty children with ILD underwent HRCT in supine position under free-respiratory conditions during scanning. Children under 5 years old were sedated with chloral hydrate and the scanning scope was from the lung apex to the diaphragm. In children older than 5 years old, scans ... more

M.L. He; H. Lai; Y. Cao; Y.Z. Shuai; S.C. Yu
04/03/2014
Body mass index; Children; Obesity; Renal function; Serum creatinine

This study was designed to analyze the relationship between serum creatinine and body mass index in children in Xinjiang, China. We used a stratified sampling method to select 5222 children aged 6-17 years in 3 areas in Xinjiang and then measured serum creatinine with an enzymatic method. Our analysis showed that the mean serum creatinine of the various age groups differed, and the ... more

X.M. Li; Y.T. Ma; X. Xie; Y.N. Yang; X.M. Li; Y.Y. Zheng
06/01/2015
Case-control study; Children; Risk factor; Urinary calculus

The incidence of urinary calculus (UC) is very high in Uyghur children in the Kashi region of Xinjiang, China, which seriously affects the growth and life quality of these children. This study was aimed at investigating the risk factors of UC in Uyghur children in Kashi region. One hundred fifteen Uyghur children (age

H.C. Wang; C. Liu; H.Y. He; M.X. Wang
03/31/2015
Children; Recombinant human granulocyte-macrophage colony-stimulating factor; rhGM-CSF; Safety; Severe burns

We explored the safety of recombinant human granulocyte-macrophage colony-stimulating factor (rhGM-CSF) for healing burns in children. Subjects were randomly assigned to two groups: the experimental group received external rhGM-CSF gel, and the control group received rhGM-CSF gel matrix components, applied to the burn surface. Neither group was given any other drugs that promote wound ... more

Y.F. Chi; J.K. Chai; H.M. Luo; Q.X. Zhang; R. Feng
01/15/2015
Adolescent; Children; PTPN22; Type 1 diabetes mellitus

Previous studies have indicated that the protein tyrosine phosphatase nonreceptor type 22 gene (PTPN22) is associated with type 1 diabetes (T1DM) in the Caucasian population. In the present study, we investigated the relationship between PTPN22 genetic polymorphisms and T1DM in Chinese children. A total of 202 children and adolescents with T1DM and 240 healthy control ... more

H.W. Liu; R.Y. Xu; R.P. Sun; Q. Wang; J.L. Liu; W. Ge; Z. Yu
10/24/2013
Children; Diabetes; Impaired fasting glucose; Prevalence of diabetes

This study was designed to estimate the prevalence of diabetes and impaired fasting glucose (IFG) in Xinjiang children in western China. Data were obtained from the Chun-Miao Project, a community-based, cross-sectional study designed to investigate the prevalence and risk factors of diabetes in children of the Chinese Uygur population in Xinjiang from February 2010 to May 2012. A total of ... more

J. Zhang; Y.T. Ma; X. Xie; Y.N. Yang; F. Liu; X.M. Li; Z.Y. Fu; X. Ma; B.D. Chen; Y.Y. Zheng; Z.X. Yu; Y. Chen
01/24/2014
Children; Immune; Obstructive sleep apnea-hypopnea syndrome; Plasma-mediated temperature-controlled radiofrequency ablation

The purpose of this study was to investigate the changes in the humoral and cellular immunity of children with obstructive sleep apnea-hypopnea syndrome and hypertrophy of tonsils before and after plasma-mediated temperature-controlled radiofrequency ablation treatment. Fifty-seven children suffering from obstructive sleep apnea-hypopnea syndrome and with hypertrophy of tonsils were ... more

Z.Y. Dai; D.Y. Huang; C.Y. Zhou
05/25/2015
C-reactive protein; Cartilage glycoprotein 39; Children; Continuous blood purification technique; Sepsis; Treatment mechanism

We analyzed disease severity, inflammation markers, and dynamic changes in cartilage glycoprotein 39 (YKL-40) and C-reactive protein (CRP) levels in children with sepsis before and after treatment with continuous blood purification (CBP). Study participants were 30 children with severe sepsis who were cured from the disease (experimental group) in the Children’s Serious Disease Center of ... more

J.P. Liu; X.W. Wang; L.P. Qie

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