Research Article

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Avian influenza virus; Chicken embryo fibroblast; H9N2; miRNA

There is limited information about microRNAs (miR­NAs) in H9N2 subtype influenza virus-infected chicken cells or tissues. In this study, 10,487,469 and 13,119,795 reads were obtained from in­fected and non-infected chicken embryo fibroblasts, respectively. Seven hundred and thirty-six and 1004 miRNAs, including mature miRNAs and precursors, were obtained from the infected and non-infected ... more

X. Peng; Q.S. Gao; L. Zhou; Z.H. Chen; S. Lu; H.J. Huang; C.Y. Zhan; M. Xiang
11/13/2015
Giant panda; Lactation; Mammary gland; miRNA

The giant panda (Ailuropoda melanoleuca) is one of the world’s most endangered mammals, and it has evolved several unusual biological and behavioral traits. During puberty, pregnancy, lactation, and involution, the mammary gland undergoes profound morphological and functional changes. A large number of microRNAs (miRNAs) have been identified to be involved in mammary gland ... more

C.D. Wang; K. Long; L. Jin; S. Huang; D.H. Li; X.P. Ma; M. Wei; Y. Gu; J.D. Ma; H. Zhang
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Breast cancer; ILIA; Insertion/deletion; miRNA; Polymorphism

The insertion/deletion polymorphism (rs3783553 TTCA/-) in the 3' untranslated region of interleukin-1A (IL1A) has been studied intensively and has been shown to affect tumor risk. We studied the frequency of the IL1A gene polymorphism rs3783553 and evaluated its relationship with breast cancer (BC). A hospital-based case-control study comprising 228 patients with histologically ... more

X. Huang; Y. Yang; Z.W. Cui; J. Wang; L.B. Gao; X. Huang; Y. Yang; Z.W. Cui; J. Wang; L.B. Gao
10/05/2018
DNA; miRNA; mRNA; Next-generation sequencing; Phalaenopsis; PhalDB

The orchid family Orchidaceae is one of the largest families of angiosperms; it includes approximately 35,000 species, displays a wide range of unique flower shapes and is a valued ornamental crop. Among the various species of orchids, the Phalaenopsis genus is the most widely commercialized among blooming potted plants. Our aim was to provide in-depth ... more

C.Y. Lee; K.K. Viswanath; J.Z. Huang; C.P. Lee; C.P. Lin; T.C. Cheng; B.C. Chang; S.W. Chin; F.C. Chen
11/30/2019
Apoptosis; Gene; Glioblastoma; miRNA

Glioblastoma is considered incurable, even with a combination of therapies (chemo and radiotherapy), and surgical resection. New therapeutic approaches are needed to improve the prognosis of patients with glioblastoma. In recent decades, research has focused on molecular biology of brain tumors. We examined the role of programmed cell death, apoptosis, through two ... more

F. Pansani; L.P. Turra; F.S.Lizarte Neto; M.Lde A. Cirino; L.F. Tirapelli; F.M. Peria; C.G.Carlotti Junior; D.Pda C. Tirapelli
08/31/2020
Alcoholism; Apoptosis; blood; Cerebral ischemia; miRNA; morphology

One of the main global causes of mortality is cerebral ischemia. Studies report that alcohol abuse causes health problems, aggravating the conditions of neurological diseases. The role of microRNAs has been highlighted in the literature as biomarkers in various types of diseases, including neurological disorders. Evidence of dysregulation of serum miRNAs related to ... more

P.C. Novais; F.S.L. Neto; M.Lde A. Cirino; L.B. Porsani; J.P. da Silva; I.S. Gula; deT. Durand; C.A.M. de Carvalho; B.C. Schimming; deF.G.S. Tazima; C.G. Carlotti; B.O. Colli; D.Pda C. Tirapelli; L.F. Tirapelli
05/31/2021
Bronchopulmonary dysplasia; Chronic lung disease; Deep sequencing; Inflammatory; miRNA

We examined the biological roles of microRNAs (miRNAs) in the pathogenesis of bronchopulmonary dysplasia (BPD). Neonatal rats were randomly assigned to hyperoxia (85% O2) and normoxia (21% O2) groups, and each group had eight neonatal. Twenty differentially expressed miRNAs were identified by deep sequencing, of which 10 were up-regulated and ... more

D. Li; H. Cheng; L. Chen; B. Wu
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Genetic analysis; Male sterility; Medicago truncatula; Tapetum

Heterosis, or enhancement through outbreeding, is one of the most promising approaches for increasing crop yield. Male sterility (MS), which promotes heterosis, has been widely applied in hybrid crop production. Medicago truncatula is a model legume species and is closely related to M. sativa, an important legume forage plant. Although the molecular mechanisms of MS in ... more

L.H. Shao; X.W. Zheng; D.X. Yi; C. Li; L.H. Shao; X.W. Zheng; D.X. Yi; C. Li
09/22/2015
Betula kirghisorum; Expression pattern; GRAS transcription factor; NaHCO3 stress; Subcellular localization

GRAS proteins are plant-specific transcription factors that are involved in the regulation of root and shoot growth. Here, we cloned BkGRAS2 from Betula kirghisorum (abbreviated to Bk) and analyzed the physicochemical properties and expression pattern of the encoded protein. BkGRAS2 had an open reading frame of 1614 bp encoding 537 amino acid residues. The deduced ... more

G.Y. Li; C.J. Yang; G.J. Liu
09/22/2015
CsICE1; Expression pattern; Real-time quantitative PCR; Tea plant

CsICE1 is thought to be involved in hardiness resistance of tea plants. Using seedling cuttings of biennial Wuniuzao in this study, the pattern of CsICE1 expression under cold temperature (4°, -5°C), drought [20% polyethylene glycol 6000 (PEG-6000)], and plant hormone [200 mg/L abscisic acid (ABA), 1 mg/L brassinolide (BR)] treatment was studied by real-time quantitative PCR. ... more

Z.T. Ding; C. Li; H. Shi; H. Wang; Y. Wang

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