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11/25/2015
CK19 mRNA; KS1/4 mRNA; LUNX mRNA; Micrometastases; Non-small cell lung cancer; RT-PCR

The expression of CK19, LUNX, and KS1/4 mRNA biomarkers was detected in the peripheral blood of non-small cell lung cancer (NSCLC) patients to investigate the feasibility of indicating lung cancer micrometastases. Micrometastases were identified in the peripheral blood of 32 NSCLC patients, 15 benign pulmonary disease (BPD) patients, and 10 healthy volunteers by ... more

L. Yan; Y. Yao; L.H. Wang; M.L. Wang; X.H. Fu
10/21/2015
Circulating tumor cell; Human telomerase reverse transcriptase; Non-small cell lung cancer; S-phase kinase-associated protein 2; Thyroid transcription factor-1

Our study aims to determine the clinical significance of human telomerase reverse transcriptase (hTERT), S-phase kinase-associated protein 2 (Skp2) and thyroid transcription factor-1 (TTF-1) mRNA expressions in peripheral blood (PB) of patients with non-small cell lung cancer (NSCLC). Real-time polymerase chain reaction was used to investigate the gene expressions of hTERT, Skp2, TTF-1 as ... more

M. Ding; X. Li; T. Qiu
10/21/2015
Adenocarcinoma; D5F3 antibody; Echinoderm microtubule associated protein like 4-anaplastic lymphoma kinase; Epidermal growth factor receptor; Non-small cell lung cancer

Echinoderm microtubule associated protein like 4-anaplastic lymphoma kinase (EML4-ALK) gene rearrangements and epidermal growth factor receptor (EGFR) mutations in non-small cell lung cancer (NSCLC) have been intensively studied. The objective of this study was to determine the clinicopathological characteristics in genotype-specific subsets of patients with NSCLC to ... more

L. Xu; J. Lei; Q.Z. Wang; J. Li; L. Wu

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