Research Article

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The association between the single nucleotide polymorphism rs762551 in the cytochrome P450 family 1, subfamily A2 gene (CYP1A2) and caffeine consumption remains controversial. We conducted a meta-analysis to clarify this potential association. Twelve studies were selected from articles retrieved from the and Google Scholar databases, and the data were analyzed to determine the ... more

S. Denden; B. Bouden; H. Khelil; J. Ben Chibani; M.H. Hamdaoui; S. Denden; B. Bouden; H. Khelil; J. Ben Chibani; M.H. Hamdaoui; S. Denden; B. Bouden; H. Khelil; J. Ben Chibani; M.H. Hamdaoui
05/13/2016
Chinese family; Hypertension; mtDNA; Mutation

Mutations in the mitochondrial genome have been found to be associated with essential hypertension. Here, we report the clinical and molecular characterization of a three-generation Han Chinese family with maternally inherited hypertension. Most strikingly, this pedigree exhibited a high penetrance of hypertension. Sequence analysis of the mitochondrial genome showed the presence of a ... more

J.F. Zhu; X. Zhang; L. Ling; J.F. Zhu; X. Zhang; L. Ling
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DNA extraction; mtDNA; Parchment; PCR; species identification

Historical parchments in the form of documents, manuscripts, books, or letters, make up a large portion of cultural heritage collections. Their priceless historical value is associated with not only their content, but also the information hidden in the DNA deposited on them. Analyses of ancient DNA (aDNA) retrieved from parchments can be used in various investigations, including, but not ... more

T. Lech; T. Lech
06/30/2021
Aflatoxin; Fungi; Host; Phylogenetics; RAPD and ISSR

Aspergillus flavus produces carcinogenic aflatoxins. This species is divided based on the type of sclerotia produced, designated as “S” for numerous small and “L” for fewer and large. “L” strains are concerning since they are prevalent in corn, peanut, rice, and soil samples. Nearly all “S” strains and approximately 70% of “L” strains produce aflatoxins. ... more

K.Ldos Reis; I.P. Barbosa-Tessmann
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Understanding the genetic diversity of different Pakistani mango varieties is important for germplasm management and varietal characterization. Microsatellites are efficient and highly polymorphic markers for comparative genome mapping, and were used in the present study to determine the genetic relatedness and variability among 15 indigenous mango cultivars (Mangifera indica L.). Overall, 181 ... more

T. Nazish; G. Shabbir; A. Ali; S. Sami-Ul-Allah; M. Naeem; M. Javed; S. Batool; H. Arshad; S.B. Hussain; K. Aslam; R. Seher; M. Tahir; M. Baber
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Animals; Goats; Pakistan; Peste-des-Petits-Ruminants; Peste-des-petits-ruminants virus; Serologic Tests

Goats are the Pakistan's fastest growing ruminants, and Pakistan is the third largest goat producer in the world after India and China. Goat meat preference is the main reason for its increased demand. In the country, there are 25 goat breeds and two wild relatives such as Mark and Goats. At present, Pakistan has 53.8 million goats, according to the 2006 GOP report, and their population growth ... more

A.K. Maitlo; J.A. Ujan; S.A. Ujjan; M. Ruk; B.A. Memon; A.A. Mahar; A.A. Ujjan