Research Article

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We conducted a prospective study to investigate whether ERCC1 rs11615 and rs3212986 and ERCC2 rs13181 and rs1799793 gene polymorphisms could serve as potential biomarkers for the prognosis of gastric cancer. Between January 2010 and December 2012, 246 patients with pathologically proven gastric cancer who were receiving platinum-based chemotherapy were recruited from the ... more

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Gastric cancer; MicroRNA; Polymorphism; Review

MicroRNAs (miRNAs) are a class of small non-coding RNA molecules of about 22 nucleotides in length. miRNAs are highly conserved in both plants and animals, and function as gene regulators by binding to the 3'-untranslated region of target mRNAs for cleavage and/or translational repression. miRNA biogenesis, stability, and regulation of expression are strongly sequence dependent. Sequence ... more

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Chinese population; Gastric cancer; Polymorphism; XPG

We conducted a case-control study to investigate the role of three common single nucleotide polymorphisms (SNPs) in the xeroderma pigmentosum complementation group G (XPG) gene (rs2094258, rs751402 and rs17655) in the development of gastric cancer in a Chinese population. Between January 2012 and December 2014, samples from a total of 177 patients with gastric cancer and 237 ... more

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Gastric cancer; Interleukin-17; Polymorphism; rs2275913

The purpose of this hospital-based case-control study was to assess whether the interleukin (IL)-17 rs2275913 genetic variation can influence susceptibility to gastric cancer. Samples from a total of 202 gastric cancer patients and 237 controls were collected from the Linyi People’s Hospital between March 2013 and March 2015. The IL-17 rs2275913 gene polymorphism was identified by ... more

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Gastric cancer; miR-146a; miR-149; miR-196a2; Polymorphism

Here, we performed a case-control study to investigate the role of miR-146a, miR-149, and miR-196a2 polymorphisms in the development of gastric cancer using a hospital-based case-control design. A total of 186 gastric cancer patients and 186 control subjects were enrolled from Ren Ji Hospital between January 2012 and October 2014. MicroRNAs miR-146a, miR-149, and miR-196a2 were genotyped ... more

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ERCC5; Non-small cell lung cancer; SNPs; XRCC1

We aimed to assess the role of polymorphisms of the XRCC1 Arg194Trp, XRCC1 Arg399Gln, ERCC5 His1104Asp, and ERCC5 His46His genes on clinical outcomes of advanced non-small cell lung cancer (NSCLC) patients receiving platinum-based chemotherapy regimens. A total of 378 NSCLC patients were asked to participate within 1 month after diagnosis between January 2005 and January 2006, and they ... more

D. Liu; J. Wu; G.Y. Shi; H.F. Zhou; Y. Yu
03/31/2016
ERCC5; Gastric cancer; Polymorphism

We conducted a hospital-based case-control study to investigate the association between 3 common SNPs in the ERCC5 gene (rs1047768, rs751402, and rs17655) and the risk of developing gastric cancer. Between January 2013 and December 2014, samples were collected from 216 gastric cancer patients and 216 control subjects. ERCC5 rs1047768, rs751402, and rs17655 polymorphisms ... more

R.J. Li; M. Li; G.J. Liu; Y.W. Guo; H. Bai; P. Xiao; J.Z. Mei; R.J. Li; M. Li; G.J. Liu; Y.W. Guo; H. Bai; P. Xiao; J.Z. Mei; R.J. Li; M. Li; G.J. Liu; Y.W. Guo; H. Bai; P. Xiao; J.Z. Mei
08/26/2016
Chinese population; ERCC5; Gastric cancer; Polymorphism

Our study aimed to investigate the role of 2 ERCC5 promoter SNPs (rs2094258 and rs751402) in the development of gastric cancer in the Chinese population. The present hospital-based case-control study consisted of 155 patients with gastric cancer and 246 healthy controls recruited between March 2012 and December 2014. Genotyping for the rs2094258 and rs751402 polymorphic sites was carried ... more

L.Q. Yang; Y. Zhang; H.F. Sun; L.Q. Yang; Y. Zhang; H.F. Sun
04/28/2016
16S rDNA; Pathogenicity island; Polymerase chain reaction; Polymorphism

Chromobacterium violaceum is a free-living Gram-negative bacillus usually found in the water and soil in tropical regions, which causes infections in humans. Chromobacteriosis is characterized by rapid dissemination and high mortality. The aim of this study was to detect the genetic variability among C. violaceum type strain ATCC 12472, and seven isolates from the ... more

A.C. Santini; J.T. Magalhães; J.C.M. Cascardo; R.X. Corrêa; A.C. Santini; J.T. Magalhães; J.C.M. Cascardo; R.X. Corrêa; A.C. Santini; J.T. Magalhães; J.C.M. Cascardo; R.X. Corrêa

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