Research Article

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It has been suggested that the xeroderma pigmentosum complementation group G (XPG) gene Asp1104His polymorphism is linked to susceptibility to lung cancer. However, the results from the published studies are contradictory rather than conclusive. With this meta-analysis, we aimed to achieve a better understanding of the effects of the XPG gene Asp1104His polymorphism on ... more

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Cytochrome P450; Lung cancer; Meta-analysis; Polymorphism; Risk

The aim of this meta-analysis was to assess the association between a polymorphism (-3860 G > A) in the cytochrome P450 1A2 (CYP1A2) gene and lung cancer susceptibility. Relevant studies were retrieved from the PubMed and EMBase databases, and additionally evaluated for conformance with the inclusion criteria. The odds ratios (ORs) and their 95% confidence intervals (95%CIs) ... more

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L. Yan; M. Wu; N. Ba; G. Shi; L. Wang; H. Zhang; L. Yan; M. Wu; N. Ba; G. Shi; L. Wang; H. Zhang
04/07/2016
A1298C; C677T; Lung cancer; Meta-analysis; MTHFR; Polymorphisms

Results from previous studies on the association between methylenetetrahydrofolate reductase (MTHFR) polymorphisms C677T and A1298C and lung cancer have been conflicting. The aim of this meta-analysis was to clarify the effect of MTHFR polymorphisms on the risk of lung cancer. An electronic search of PubMed, EMBASE, the Cochrane library, and the China Knowledge Resource ... more

Y. Yang; L.J. Yang; M.Z. Deng; Y.Y. Luo; S. Wu; L. Xiong; D. Wang; Y. Liu; H. Liu; Y. Yang; L.J. Yang; M.Z. Deng; Y.Y. Luo; S. Wu; L. Xiong; D. Wang; Y. Liu; H. Liu; Y. Yang; L.J. Yang; M.Z. Deng; Y.Y. Luo; S. Wu; L. Xiong; D. Wang; Y. Liu; H. Liu
06/03/2016
Arg194Trp; Arg280His; Arg399Gln; Pancreatic cancer; Polymorphism; XRCC1

We conducted a case-control study to assess the role of the XRCC1 Arg399Gln, Arg280His, and Arg194Trp gene polymorphisms in pancreatic cancer susceptibility in a Chinese population. A total of 152 patients diagnosed with pancreatic cancer and 264 control subjects were enrolled in this study between March 2012 and October 2014. XRCC1 Arg399Gln, Arg280His, and Arg194Trp were genotyped ... more

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10/05/2016
Arg194Trp; Arg280His; Arg399Gln; Laryngeal cancer; Polymorphism; XRCC1

Laryngeal cancer is the major malignant tumor affecting the upper respiratory tract. Previous studies have reported on the association between XRCC1 genetic polymorphisms and risk of laryngeal cancer, but with conflicting results. In this study, we attempted to assess the association between XRCC1 Arg194Trp, Arg280His and Arg399Gln polymorphisms and risk of laryngeal ... more

W.Q. Wu; L.S. Zhang; S.P. Liao; X.L. Lin; J. Zeng; D. Du; W.Q. Wu; L.S. Zhang; S.P. Liao; X.L. Lin; J. Zeng; D. Du
09/09/2016
Chinese population; Gastric cancer; Polymorphism; XRCC1

We carried out a hospital-based case-control study to investigate the role of XRCC1 gene Arg399Gln, Arg280His, and Arg194Trp polymorphisms in susceptibility to gastric cancer. A total of 214 gastric cancer patients and 247 control subjects were recruited between March 2013 and March 2015, and polymorphism genotype frequencies were determined by polymerase chain reaction- ... more

S. Chen; X.C. Zhu; Y.L. Liu; C. Wang; K.G. Zhang; S. Chen; X.C. Zhu; Y.L. Liu; C. Wang; K.G. Zhang
08/26/2016
Arg194Trp; Arg399Gln; Chinese population; Glioma; Polymorphism; XRCC1

We conducted a study in a Chinese Han population to investigate the role of XRCC1 gene polymorphisms (Arg399Gln and Arg194Trp) with a risk of susceptibility to gliomas. Samples from 115 patients with gliomas and 228 control subjects were consecutively collected between March 2012 and December 2014. Genotype analysis of XRCC1 Arg399Gln and Arg194Trp was performed using ... more

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Arg194Trp; Thyroid cancer; XRCC1

Previous case-control studies having investigated the relationship between the X-ray repair cross-complementing group 1 (XRCC1) Arg194Trp polymorphism and thyroid cancer (TC) have drawn inconsistent conclusions. The current study aimed to clarify the role of this polymorphism in susceptibility to TC. An up-to-date search of PubMed and Web of Science databases was conducted, ... more

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04/29/2016
Chinese cabbage; CRTISO; Fine mapping; Molecular marker; Orange head trait; Sequence blasting

Orange inner leaves/heads is a qualitative trait in Chinese cabbage that is controlled by a single recessive gene. Orange head Chinese cabbage contain more carotenoids than its white head counterpart; hence, this trait is of interest to both researchers and consumers. In this study, we selected the orange head Chinese cabbage line 07A163 and the white head Chinese cabbage line Chiifu as ... more

C.L. Zou; Y. Zheng; P. Wang; X. Zhang; Y.H. Wang; Z.Y. Liu; H. Feng; C.L. Zou; Y. Zheng; P. Wang; X. Zhang; Y.H. Wang; Z.Y. Liu; H. Feng

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