Research Article

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Published studies on the association between the C677T and A1298C polymorphisms of the methylenetetrahydrofolate reductase (MTHFR) gene and male infertility risk are controversial. To obtain a more precise evaluation, we performed a meta-analysis based on published case-control studies. We conducted an electronic search of PubMed, EMBASE, the Cochrane Library, the Web of Science ... more

Y. Yang; Y.Y. Luo; S. Wu; Y.D. Tang; X.D. Rao; L. Xiong; M. Tan; M.Z. Deng; H. Liu; Y. Yang; Y.Y. Luo; S. Wu; Y.D. Tang; X.D. Rao; L. Xiong; M. Tan; M.Z. Deng; H. Liu; Y. Yang; Y.Y. Luo; S. Wu; Y.D. Tang; X.D. Rao; L. Xiong; M. Tan; M.Z. Deng; H. Liu
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A1298C; C677T; Lung cancer; Meta-analysis; MTHFR; Polymorphisms

Results from previous studies on the association between methylenetetrahydrofolate reductase (MTHFR) polymorphisms C677T and A1298C and lung cancer have been conflicting. The aim of this meta-analysis was to clarify the effect of MTHFR polymorphisms on the risk of lung cancer. An electronic search of PubMed, EMBASE, the Cochrane library, and the China Knowledge Resource ... more

Y. Yang; L.J. Yang; M.Z. Deng; Y.Y. Luo; S. Wu; L. Xiong; D. Wang; Y. Liu; H. Liu; Y. Yang; L.J. Yang; M.Z. Deng; Y.Y. Luo; S. Wu; L. Xiong; D. Wang; Y. Liu; H. Liu; Y. Yang; L.J. Yang; M.Z. Deng; Y.Y. Luo; S. Wu; L. Xiong; D. Wang; Y. Liu; H. Liu
03/28/2016
Genetic polymorphism; Hypertension; MTHFR; Risk factors

The association of the methylenetetrahydrofolate reductase (MTHFR) C677T gene polymorphism and essential hypertension has been reported but with controversial results in diverse populations in Asia and Europe, thereby suggesting a dependency on ethnicity. The aim of this study was to investigate the association between the MTHFR C677T polymorphism and essential ... more

S.M. Ghogomu; N.E. Ngolle; R.N. Mouliom; B.F. Asa; S.M. Ghogomu; N.E. Ngolle; R.N. Mouliom; B.F. Asa; S.M. Ghogomu; N.E. Ngolle; R.N. Mouliom; B.F. Asa
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16S rDNA; Pathogenicity island; Polymerase chain reaction; Polymorphism

Chromobacterium violaceum is a free-living Gram-negative bacillus usually found in the water and soil in tropical regions, which causes infections in humans. Chromobacteriosis is characterized by rapid dissemination and high mortality. The aim of this study was to detect the genetic variability among C. violaceum type strain ATCC 12472, and seven isolates from the ... more

A.C. Santini; J.T. Magalhães; J.C.M. Cascardo; R.X. Corrêa; A.C. Santini; J.T. Magalhães; J.C.M. Cascardo; R.X. Corrêa; A.C. Santini; J.T. Magalhães; J.C.M. Cascardo; R.X. Corrêa
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Coronary artery disease; IL-10-1082A/G; Polymorphism

We conducted a case-control study to investigate the association between IL-10-G1082A (rs1800896) polymorphism and the development of coronary artery disease (CAD) in the Chinese population. We recruited 295 CAD patients and 355 healthy controls from the Fifth Affiliated Hospital of Zhengzhou University between April 2012 and December 2014. Subjects were genotyped for IL-10 ... more

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ERCC1; ERCC2; Gastric cancer; Polymorphism; Treatment outcome

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D.L. Zheng; G.D. Tang; Y.N. Chen; T. Zhang; M.B. Qin; D.L. Zheng; G.D. Tang; Y.N. Chen; T. Zhang; M.B. Qin; D.L. Zheng; G.D. Tang; Y.N. Chen; T. Zhang; M.B. Qin
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Bladder cancer; CYP1A2; Polymorphism; Risk

To date, no study has investigated the association between CYP1A2-163C/A polymorphism and bladder cancer risk in a Chinese population. Here, we extracted genomic DNA from peripheral white blood cells, and differentiated CYP1A2 alleles by polymerase chain reaction-based restriction fragment length polymorphism methods. Differences in genotype frequencies between the cases ... more

Y.L. Song; L. Wang; J.C. Ren; Z.H. Xu; Y.L. Song; L. Wang; J.C. Ren; Z.H. Xu; Y.L. Song; L. Wang; J.C. Ren; Z.H. Xu
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Although various individual studies have evaluated the correlation between monoamine oxidase B (MAOB), polymorphism, and Parkinson’s disease (PD), the results remain inconclusive. Therefore, we performed a meta-analysis in the Chinese population to provide comprehensive data on the association between the MAOB polymorphism and PD. Eligible studies were identified via databases such as ... more

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Although various individual studies have evaluated the correlation between monoamine oxidase B (MAOB), polymorphism, and Parkinson’s disease (PD), the results remain inconclusive. Therefore, we performed a meta-analysis in the Chinese population to provide comprehensive data on the association between the MAOB polymorphism and PD. Eligible studies were identified via databases such as ... more

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