Research Article

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CYP1A1; Estrogen receptor β; GSTM1; GSTT1; p53; Progesterone receptor

In healthy women, intra- and extracellular controls prevent the attachment and proliferation of ectopic endometrial cells. During endometriosis, abnormalities in these control mechanisms permit the survival of endometrial cells, their subsequent attachment to the peritoneal cavity, and disease progression. These abnormal cells cause invasion of tissues and induce an inflammatory response ... more

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Meta-analysis; Monoamine oxidase B; Parkinson’s disease; Polymorphism

Although various individual studies have evaluated the correlation between monoamine oxidase B (MAOB), polymorphism, and Parkinson’s disease (PD), the results remain inconclusive. Therefore, we performed a meta-analysis in the Chinese population to provide comprehensive data on the association between the MAOB polymorphism and PD. Eligible studies were identified via databases such as ... more

J.J. Liu; W. Wang; M. Meng; C.S. Liang; J.W. Zhang
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Meta-analysis; Monoamine oxidase B; Parkinson’s disease; Polymorphism

Although various individual studies have evaluated the correlation between monoamine oxidase B (MAOB), polymorphism, and Parkinson’s disease (PD), the results remain inconclusive. Therefore, we performed a meta-analysis in the Chinese population to provide comprehensive data on the association between the MAOB polymorphism and PD. Eligible studies were identified via databases such as ... more

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Interleukin-6; Meta-analysis; Polymorphism; Psoriasis

Previous studies examining the association between interleukin-6 (IL-6) -174G/C polymorphism and psoriasis risk have produced inconsistent results. The aim of this study was to offer a comprehensive review of the association between IL-6 -174G/C polymorphism and psoriasis risk through a meta-analysis. Literature search of PubMed and Embase databases was conducted to identify all eligible ... more

G. Nie; C.L. Xie; Y.J. Cao; M.M. Xu; X. Shi; A.L. Zou; J.H. Qi; G. Nie; C.L. Xie; Y.J. Cao; M.M. Xu; X. Shi; A.L. Zou; J.H. Qi
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Cytochrome P450; Lung cancer; Meta-analysis; Polymorphism; Risk

The aim of this meta-analysis was to assess the association between a polymorphism (-3860 G > A) in the cytochrome P450 1A2 (CYP1A2) gene and lung cancer susceptibility. Relevant studies were retrieved from the PubMed and EMBase databases, and additionally evaluated for conformance with the inclusion criteria. The odds ratios (ORs) and their 95% confidence intervals (95%CIs) ... more

J. Ren; B.Z. He; T.S. Zhang; S.P. Lu; T. Yan; J. Ren; B.Z. He; T.S. Zhang; S.P. Lu; T. Yan
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Breast cancer; GSTP1; Meta-analysis; Polymorphism

Breast cancer (BC) is the most widespread cause of cancer-related deaths in women. Many published studies have assessed the association between the glutathione S-transferase P1 (GSTP1) rs1695 polymorphism and BC risk. However, the effect of the GSTP1 rs1695 polymorphism on BC risk has remained controversial. Therefore, this meta-analysis was conducted to obtain a ... more

M. Kuang; W. Xu; C.X. Cao; L.L. Shen; J. Chang; X.L. Zhang; J.F. Chen; C.J. Tang; M. Kuang; W. Xu; C.X. Cao; L.L. Shen; J. Chang; X.L. Zhang; J.F. Chen; C.J. Tang
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Meta-analysis; Polycystic ovary syndrome; Polymorphism; Tumor necrosis factor alpha

Previous studies have suggested that the tumor necrosis factor alpha (TNF-α) gene 308G/A polymorphism may be associated with polycystic ovary syndrome (PCOS) risk. However, this relationship is controversial. The present meta-analysis aimed to evaluate the correlation between the TNF-α308G/A polymorphism and susceptibility to PCOS. A systematic ... more

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Interleukin-10; Meta-analysis; Pediatric asthma; Polymorphism

The results of previous epidemiological studies exploring the relationship between interleukin-10 (IL-10) promoter polymorphisms and susceptibility to pediatric asthma are not consistent. Therefore, we have performed a systematic review and meta-analysis to provide a more convincing conclusion. Odds ratios (OR) with their 95% confidence intervals (CIs) were used to evaluate the ... more

Z.Y. Huang; B.J. Cheng; Y. Wan; C. Zhou; Z.Y. Huang; B.J. Cheng; Y. Wan; C. Zhou
04/28/2016
16S rDNA; Pathogenicity island; Polymerase chain reaction; Polymorphism

Chromobacterium violaceum is a free-living Gram-negative bacillus usually found in the water and soil in tropical regions, which causes infections in humans. Chromobacteriosis is characterized by rapid dissemination and high mortality. The aim of this study was to detect the genetic variability among C. violaceum type strain ATCC 12472, and seven isolates from the ... more

A.C. Santini; J.T. Magalhães; J.C.M. Cascardo; R.X. Corrêa; A.C. Santini; J.T. Magalhães; J.C.M. Cascardo; R.X. Corrêa; A.C. Santini; J.T. Magalhães; J.C.M. Cascardo; R.X. Corrêa
04/28/2016
Coronary artery disease; IL-10-1082A/G; Polymorphism

We conducted a case-control study to investigate the association between IL-10-G1082A (rs1800896) polymorphism and the development of coronary artery disease (CAD) in the Chinese population. We recruited 295 CAD patients and 355 healthy controls from the Fifth Affiliated Hospital of Zhengzhou University between April 2012 and December 2014. Subjects were genotyped for IL-10 ... more

K. Liang; S.R. Dong; H. Peng; K. Liang; S.R. Dong; H. Peng; K. Liang; S.R. Dong; H. Peng

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