Research Article

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Insulin-like growth factor binding protein-6 (IGFBP-6) is a member of the IGFBP family, which is known to be a key factor in regulating the effect of insulin-like growth factor-2 (IGF-2) on the animal growth and development. Gene sequences of 3'-untranslated regions (UTR) and exon 4 of IGFBP-6 may influence the expression and proteolysis of IGFBP-6. In this study, 551 bp of the ... more

X.B. Fang; S.C. Liu; Q.Y. Wu; S.M. Li; Y.Y. Cheng; H.Y. Fu; C. Lu; D. Su; H. Yu; L.L. Hao
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APM1; Disorders of lipid metabolism; HDCP; SNPs

The aim of this study was to determine whether single nucleotide polymorphisms (SNPs) in APM1 contribute to disorders of lipid metabolism in hypertensive disorder complicating pregnancy (HDCP). The study included 178 pregnant women with HDCP and 243 healthy pregnant controls. Using PCR-restriction fragment length polymorphism, we detected the frequencies of genotypes, alleles, ... more

Y. Wang; R.X. Liu; H. Liu
10/09/2015
Genetic diversity; Haplo-block structure; SNPs; Village chickens

This study investigated the haplo-block structure, haplotype sharing, and diversity in extensively raised chicken populations of Southern Africa. Two hundred ninety village chickens from Malawi (N = 30), South Africa (N = 132), and Zimbabwe (N = 128) were included in the study, from which 649, 2104, and 2442 haplo-blocks were observed, respectively. The majority of haplo-blocks were ... more

K.S. Khanyile; E.F. Dzomba; F.C. Muchadeyi
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Duck; Fatty acid composition; SCD1; Serum biochemical levels; SNPs

Stearoyl-coenzyme A desaturase 1 (SCD1) is the key limiting enzyme in the synthesis of monounsaturated fatty acids, and plays a crucial role in the regulation of oleic acid. In this study, 165 ten-week-old Cherry Valley ducks were used to investigate single nucleotide polymorphisms (SNPs) in the 5' regulatory region of the SCD1 gene, and their associations with duck serum ... more

W.G. Li; Y.Y. Zhang; D.D. Wang; W.G. Li; Y.Y. Zhang; D.D. Wang
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Heat stress; MBV; Milk yield; Prolactin; SNPs

The association of single nucleotide polymorphisms (SNPs) within genes of the prolactin (PRL), growth hormone (GH) and insulin-like growth factor-I (IGF1) pathways with 305-day milk yield (MY305) were evaluated in heat-stressed Holstein cows. Ambient temperature and relative humidity were used to calculate a temperature-humidity index (THI), which revealed that ... more

H. Cordero; M.A.Sanchez Castro; Z. Algandar; L. Nevarez; G. Rincon; J.F. Medrano; S.E. Speidel; R.M. Enns; M.G. Thomas
02/27/2018
Capture-Seq; drought tolerance; Genotyping by Sequencing; Oryza sativa L; RNA-seq; SNPs

Breeding for water-deficit tolerance is fundamental to guarantee the sustainability of upland rice production, mainly due to the possibility of an increased frequency of drought episodes due to climate change. This work aimed to identify single nucleotide polymorphism (SNP) markers, derived from RNA sequencing (RNA-Seq), genome-wide association study (GWAS) and ... more

A.Faria Vieira; G.Feresin Pantalião; F.Martins Abreu; R.Dias Silveira; A.Letycia Ba Garcia; L.Gomide Neves; R.Pereira Vianello; A.Pereira Castro; C. Brondani
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Genetic association; Genotyping; Maternal line; SNPs; Sus scrofa domesticus

MC4R, FABP3 and DGAT1 are important genes related to productive and reproductive traits in pigs, such as food intake, growth rate, back fat thickness reduction and lactation. Selection of pigs for lean meat production may lead to losses in reproductive charcters because reduction of backfat thickness and low feed intake during the lactation phase ... more

V.S. Gondim; J.S. Soares; N.A.H. Lugo; N.B. Stafuzza; G.S. Vieira; R.R. Aspilcueta-Borquis; L.A.F. Pascoal; A.C.P. Silveira; H. Tonhati; R.C. Antunes
06/30/2020
Copy number of variations; Insertions / deletions; Ovis aries; Sheep; SNPs

We report the whole ram genome of Jordanian Awassi (Ovis aries), screened using the power of Illumina HiSeq sequencing technology, providing insights into the ram's genomic structure. Generated data will help in the assessment of naturally occurring genetic variation and population structure of this sheep breed using different structure variation markers. ... more

N. Haddad; H. Migdadi; R. Al-Atiyat; K. Jawasre; S. Awabdeh; W. Obeidat; R. AlOmari; M. Aldamra; H. Ababneh; M.J. Tabbaa; M. Brake; M. Farooq
09/28/2015
Diagnosis; Enzyme-linked immunospot; Meta-analysis; Tuberculous pleurisy

Current methods for diagnosing tuberculous pleurisy are poor. Some studies have explored the diagnostic value of a pleural effusion enzyme-linked immunospot (ELISPOT) assay, but its accuracy remains controversial. Therefore, we performed a meta-analysis of the existing evidence on the ability of the ELISPOT assay to diagnose tuberculous pleurisy. We systematically searched PubMed, Google ... more

Z.Z. Li; W.Z. Qin; L. Li; Q. Wu; Y.J. Wang
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Chronic obstructive pulmonary disease; Gene polymorphism; Meta-analysis; Vitamin D-binding protein

Gene polymorphism of vitamin D-binding protein (VDBP) correlates with chronic obstructive pulmonary disease (COPD), but the results remain inconclusive. We aimed to explore the association between VDBP gene polymorphism and COPD. We searched MEDLINE, Embase, Web of Science, and China National Knowledge Infrastructure for publications addressing the association between VDBP gene ... more

Y.L. Wang; H. Kong; W.P. Xie; H. Wang

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