Research Article

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10/24/2016
Bacterial killing; CD209a; Helicobacter pylori; LECT2; Macrophages; NF-κB

Helicobacter pylori employs unique methods to colonize the stomach, which induces chronic inflammation. It is also able to avoid eradication by macrophages and other immune cells. Leukocyte cell-derived chemotaxin 2 (LECT2), a multi-functional cytokine involved in many pathological conditions, has recently been shown to activate macrophages via the CD209a ... more

H.X. Shen; L. Li; Q. Chen; Y.Q. He; C.H. Yu; C.Q. Chu; X.J. Lu; J. Chen
11/03/2016
ICAM-1; IL-6; IL-8; Myocardial ischemia-reperfusion; NF-κB; Total peony glycoside

Early recovery of myocardial perfusion is beneficial for myocardial ischemia. However, ischemia-reperfusion (I/R) may exacerbate myocardial injury. Research shows that total peony glucoside (TPG) can inhibit ischemic myocardial cell apoptosis. However, whether it can ameliorate I/R injury remains poorly understood. This study explored the effect of TPG pretreatment ... more

L. Lu; P. Wei; Y. Cao; Q. Zhang; M. Liu; X.D. Liu; Z.L. Wang; P.Y. Zhang; L. Lu; P. Wei; Y. Cao; Q. Zhang; M. Liu; X.D. Liu; Z.L. Wang; P.Y. Zhang
11/21/2016
Cell proliferation; Clone formation; Hypoxia; Periodontal ligament stem cells

There is high incidence of periodontal disease in high-altitude environments; hypoxia may influence the proliferation and clone-forming ability of periodontal ligament stem cells (PDLSCs). The MAPK signaling pathway is closely correlated with cell proliferation, differentiation, and apoptosis. Thus, we isolated and cultured PDLSCs under hypoxic conditions to ... more

Y. He; C.X. Jian; H.Y. Zhang; Y. Zhou; X. Wu; G. Zhang; Y.H. Tan; Y. He; C.X. Jian; H.Y. Zhang; Y. Zhou; X. Wu; G. Zhang; Y.H. Tan
09/28/2015
ATP; ImmuKnow assay; Prognosis; Renal carcinoma

This study aimed to explore the clinical value of the CD4+ T cell ATP levels in patients with renal cell carcinoma through the application of the ImmuKnowTM-Cylex® assay. We recruited 104 patients with renal cancer who had undergone surgery at Fuzhou General Hospital from March 2009 to June 2012, and were subsequently treated by dendritic cell and ... more

K. Zheng; J.P. Zhang; J.M. Tan; W.Z. Wu; S.L. Yang; D.D. Ke
12/17/2015
IL-6; miR-31; NF-κB; Peripheral blood mononuclear cells; TNF-α; Tuberculosis

We investigated the diagnostic values of microRNA-31 in peripheral blood mononuclear cells (PBMCs) for pediatric pulmonary tuberculosis in Chinese patients. Sixty-five children with TB were selected for this study, which was conducted at the Department of Infectious Diseases People’s Hospital of Laiwu City between December 2013 and December 2014. Sixty healthy children, selected in ... more

J.X. Wang; J. Xu; Y.F. Han; Y.B. Zhu; W.J. Zhang
05/09/2016
Advanced glycation end-products; Chondrocytes; Matrix metalloproteinase-9; NF-κB; Reactive oxygen species; TGF-β

Peroxisome proliferator-activated receptor is closely associated with the pathogenesis of osteoarthritis. The level of exogenous advanced glycation end-products (AGEs) in articular cartilage is highly associated with the severity of osteoarthritic lesions. However, their interactions and role in promoting osteoarthritisprogression remain unclear. Here, we investigated the effect of AGEs ... more

J. Wang; G. Wang; G.W. Sun; J. Wang; G. Wang; G.W. Sun
10/17/2016
Arf; Endothelial barrier function; Heart failure; IL-1β; SC514

To preliminarily clarify the mechanism of cardiac microvascular endothelial barrier function leading to heart failure, primary HMVEC-D cells were selected and cultured for amplification. The cells were infected with adenovirus vector containing the ADP-ribosylation factor 6 (Arf6) Q67L gene. Full-length and functional fragments of myeloid differentiation ... more

W. Dong; G.N. Zhang; S.H. Gao; W. Dong; G.N. Zhang; S.H. Gao; W. Dong; G.N. Zhang; S.H. Gao
11/21/2016
Comparative transcriptome; De novo assembly; Illumina sequencing; Lymph organ; Procambarus clarkii; White spot syndrome virus

The red swamp crayfish (Procambarus clarkii) is one of the most economically important farmed aquatic species in China. Compared with its relatively well-known antibacterial and antifungal mechanisms, the antiviral mechanism is still unclear. We used Illumina-based RNA sequencing and bioinformatic technology to obtain high-quality sequence reads from the ... more

Z.Q. Du; Z.Q. Du
11/03/2016
Age distribution; Cervical cancer; Human papilloma virus; Multiple infection; Subtype distribution

The aim of this study was to examine the subtype distribution of human papilloma virus (HPV) in women in the Shaanxi Province of China. A DNA chip, along with polymerase chain reaction amplification and reverse dot blot technology, was adopted to analyze the HPV genotypes of 22,937 cases of cervical cell specimens. The HPV infection ... more

J. Li; Y.Y. Wang; X.F. Tian; X. Nan; T. Yan; P. Wang; Y.L. Fu; G.Q. Wang
11/03/2016
Gestational diabetes mellitus; Meta-analysis; PPARs; Pro12Ala polymorphism

The relationship between the Pro12Ala polymorphism of PPARγ and the risk of gestational diabetes mellitus remains unresolved. Here, we attempted to resolve this inconsistency. Case-control studies pertaining to the effect of the Pro12Ala polymorphism in the PPARγ protein and risk of gestational diabetes mellitus were extracted from the ... more

H.L. Shuai; X.Z. Lin; D.L. Chen; P. Li; X. Luo

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